{"id":"W2909777411","doi":"10.1248/bpb.b19-00346","title":"Phenylbutyrate Ameliorates High-Fat Diet-Induced Obesity <i>via</i> Brown Adipose Tissue Activation","year":2019,"lang":"en","type":"article","venue":"Biological and Pharmaceutical Bulletin","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"National Research Foundation of Korea; Korea Health Industry Development Institute; National Research Foundation","keywords":"PRDM16; Endocrinology; Internal medicine; Brown adipose tissue; Adipose tissue; Thermogenin; Metabolic syndrome; Phenylbutyrate; Phosphofructokinase; Glycolysis; Obesity; Adipocyte; Chemistry; Biology; Medicine; Metabolism","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001531559,0.0008715991,0.0006675483,0.0004943037,0.0002335123,0.0002819381,0.0002844973,0.0003953592,0.00190636],"category_scores_gemma":[0.00007687652,0.0001866704,0.0005150911,0.0002913979,0.0004433302,0.0003401311,0.0002477511,0.001606078,0.0003399179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002311569,"about_ca_system_score_gemma":0.0004403293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001052763,"about_ca_topic_score_gemma":0.001763793,"domain_scores_codex":[0.999893,0.00001656676,0.0000112045,0.00001734151,0.00002518422,0.00003673688],"domain_scores_gemma":[0.9999226,0.000004225328,0.00002661291,0.00000735262,0.000009407723,0.00002979004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0033483,0.001084049,0.0004052157,0.0003041626,0.00004398331,0.0001585945,0.0000269815,0.0001966036,0.9837061,0.0002196357,0.000335959,0.01017047],"study_design_scores_gemma":[0.0006590585,0.008999242,0.009089063,0.00006019535,0.0002141242,0.0003380734,0.0001411778,0.001787322,0.9714887,0.0003071188,0.006892421,0.00002347543],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9815307,0.007039348,0.005665109,0.0009192122,0.0004022848,0.0001326487,0.000764513,0.000645545,0.00290071],"genre_scores_gemma":[0.9830824,0.006224658,0.002714235,0.000417838,0.0000826964,0.0001642235,0.0009632333,0.00008858499,0.006262023],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00190636,"threshold_uncertainty_score":0.006377399,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04044874440929733,"score_gpt":0.3015486407758765,"score_spread":0.2610998963665792,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}