{"id":"W2909785500","doi":"10.1007/978-1-4939-8988-1_20","title":"Genetic Models of Calpain Deficiency and Ectopic Expression","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Calpain Protease Function and Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research","keywords":"Calpain; Ectopic expression; Biology; Gene; Transgene; Recombinant DNA; Genotype; Mutation; Cell biology; Function (biology); Genetics; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005616663,0.001729633,0.0007349818,0.002516635,0.0007064198,0.00113207,0.002534745,0.001980414,0.004461521],"category_scores_gemma":[0.0005570331,0.0009438143,0.001072115,0.001187342,0.001606396,0.000708041,0.001063566,0.003554655,0.001884783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001214741,"about_ca_system_score_gemma":0.0007670837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00134565,"about_ca_topic_score_gemma":0.002023911,"domain_scores_codex":[0.9990436,0.00009648843,0.0001413093,0.0002518503,0.0003299339,0.0001367926],"domain_scores_gemma":[0.9989373,0.0002763388,0.0003453827,0.0001696438,0.00006258502,0.0002086764],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002410984,0.0001011568,0.0000858127,0.00007922078,0.00001841084,0.0002425324,0.0000391873,0.0003548005,0.9930622,0.004095982,0.000239505,0.001440038],"study_design_scores_gemma":[0.0001390086,0.000142478,0.0005341095,0.00001916328,0.00006443912,0.000703448,0.00003940437,0.002439118,0.9868184,0.0007342312,0.008344683,0.00002140438],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.817333,0.004326421,0.1451752,0.002524413,0.001364426,0.001388586,0.01033759,0.003626547,0.01392372],"genre_scores_gemma":[0.8817483,0.003233753,0.0718519,0.0004907676,0.0001021684,0.001465477,0.004575272,0.001019175,0.03551326],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004461521,"threshold_uncertainty_score":0.0149253,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01226159725633174,"score_gpt":0.3279160232729696,"score_spread":0.3156544260166378,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}