{"id":"W2909785500","doi":"10.1007/978-1-4939-8988-1_20","title":"Genetic Models of Calpain Deficiency and Ectopic Expression","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Calpain Protease Function and Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research","keywords":"Calpain; Ectopic expression; Biology; Gene; Transgene; Recombinant DNA; Genotype; Mutation; Cell biology; Function (biology); Genetics; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004834743,0.0001055392,0.0001662744,0.00008962025,0.00001569319,0.000003360864,0.00008777964,0.0002167397,0.00002323798],"category_scores_gemma":[0.00009461428,0.00009248008,0.0000526625,0.00009453396,0.00008266926,0.000001829019,0.0001041097,0.00006883492,0.000001124636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000709325,"about_ca_system_score_gemma":0.00002686131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001619633,"about_ca_topic_score_gemma":0.000002648078,"domain_scores_codex":[0.9986964,0.0005530148,0.0002241819,0.0003274464,0.00004648103,0.000152502],"domain_scores_gemma":[0.9995585,0.00002823031,0.00007250906,0.000271619,0.00003401772,0.00003514454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003240561,0.00002409834,0.007253938,0.00002509373,0.000005133584,7.52331e-7,0.0000210824,0.001001823,0.9809793,0.001171146,0.000006689377,0.009478504],"study_design_scores_gemma":[0.000676578,0.000316992,0.004569601,0.00001997092,0.000007420531,0.00001496893,0.00003477004,0.004690573,0.9776608,0.01051416,0.001320041,0.0001741595],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.4687105,0.001185698,0.529498,0.00001727486,0.00007879523,0.0001497998,0.000001297178,0.000003416942,0.0003552361],"genre_scores_gemma":[0.6520181,0.00007736067,0.347598,0.000107542,0.0000180273,0.00001654555,0.00001386942,0.00001090603,0.0001395763],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.1833077,"threshold_uncertainty_score":0.3771228,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01226159725633174,"score_gpt":0.3279160232729696,"score_spread":0.3156544260166378,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}