{"id":"W2910129845","doi":"10.1038/s41467-018-08163-0","title":"Neuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of CNS-derived antigens and immune cells","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"Lymphatic System and Diseases","field":"Medicine","cited_by":205,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Institutes of Health; National Cancer Institute; National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; University of Wisconsin Carbone Cancer Center; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; American Heart Association","keywords":"Neuroinflammation; Immune system; Lymphangiogenesis; Antigen; Medicine; Biology; Inflammation; Immunology; Cancer research; Pathology; Cancer; Metastasis; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002198924,0.0004648622,0.000253138,0.000707838,0.0003369854,0.0007734004,0.0002292532,0.0003289563,0.002839812],"category_scores_gemma":[0.0003374157,0.0001804967,0.0002357282,0.00028488,0.0004458255,0.0007047048,0.000568145,0.0008265301,0.00065388],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005315476,"about_ca_system_score_gemma":0.0003714979,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005524647,"about_ca_topic_score_gemma":0.0005790311,"domain_scores_codex":[0.9998276,0.00003792291,0.00001084584,0.0000356764,0.0000345373,0.00005329058],"domain_scores_gemma":[0.9997241,0.00003581803,0.0001058521,0.0000269497,0.00002962277,0.00007759276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004728122,0.00003390895,0.00361753,0.0002308242,0.00001133721,0.001258509,0.0001373773,0.0001850436,0.9872836,0.0007459185,0.0001258194,0.005897431],"study_design_scores_gemma":[0.0001081213,0.0007564175,0.08463736,0.0001728554,0.00007127284,0.006753645,0.001145746,0.00312224,0.889419,0.001199044,0.01258429,0.0000299557],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9816713,0.005277523,0.007844327,0.0002747227,0.00004655998,0.00007115384,0.0002860682,0.0001299646,0.00439841],"genre_scores_gemma":[0.9926156,0.001790413,0.002799387,0.00006024738,0.00003190299,0.00004210829,0.00009249229,0.00001801337,0.002549881],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002839812,"threshold_uncertainty_score":0.009500086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01409218006098191,"score_gpt":0.2717327493865819,"score_spread":0.2576405693256,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}