{"id":"W2910130172","doi":"10.17952/35eps.2018.178","title":"1,5-Benzothiazepinone and arylazepinone dipeptide mimetics as local constraints in peptidomimetic design","year":2018,"lang":"en","type":"article","venue":"Proceedings of the 35th European Peptide Symposium","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Peptidomimetic; Dipeptide; Computer science; Chemistry; Peptide; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004223792,0.0004107043,0.0006480681,0.0001875081,0.0002398243,0.0005302088,0.0005739103,0.0003062197,0.001604033],"category_scores_gemma":[0.0005500577,0.0003129928,0.000151377,0.00023427,0.000375228,0.0005314157,0.0006672188,0.0006589018,0.0005169429],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003572219,"about_ca_system_score_gemma":0.0003232882,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000281703,"about_ca_topic_score_gemma":0.001073669,"domain_scores_codex":[0.9998235,0.00006080061,0.00001169144,0.00002722314,0.0000514041,0.00002547455],"domain_scores_gemma":[0.9998523,0.00006346362,0.00003438041,0.00001215323,0.00001254657,0.00002525627],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009142024,0.0001531691,0.0005320096,0.0005383265,0.00004175618,0.0003414161,0.00009921476,0.1198052,0.8080333,0.01615159,0.000531541,0.05285829],"study_design_scores_gemma":[0.000531696,0.00301804,0.0009714847,0.00009815625,0.000116827,0.0005171832,0.0001511085,0.2994317,0.6631649,0.009224485,0.02268223,0.00009215203],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8061695,0.005119779,0.1764461,0.0003241707,0.00007340647,0.0002548717,0.0002228239,0.0005046695,0.01088461],"genre_scores_gemma":[0.919616,0.002488757,0.07394261,0.0001086849,0.00003543346,0.0002919115,0.0002095385,0.00007965499,0.003227432],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001604033,"threshold_uncertainty_score":0.005365968,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0075463337494351,"score_gpt":0.2115594720976846,"score_spread":0.2040131383482495,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}