{"id":"W2910430554","doi":"10.1016/j.cyto.2018.12.009","title":"Tea polyphenols protect gingival keratinocytes against TNF-α-induced tight junction barrier dysfunction and attenuate the inflammatory response of monocytes/macrophages","year":2019,"lang":"en","type":"article","venue":"Cytokine","topic":"Oral microbiology and periodontitis research","field":"Dentistry","cited_by":53,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Réseau de Recherche en Santé Buccodentaire et Osseuse; Justus Liebig Universität Gießen","keywords":"Occludin; Tight junction; Chemistry; Tumor necrosis factor alpha; Green tea extract; Pharmacology; Cytokine; Keratinocyte; Polyphenol; Periodontitis; Cell biology; Immunology; Green tea; Biochemistry; Biology; Medicine; In vitro; Internal medicine; Food science; Antioxidant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008807565,0.000218519,0.0002957465,0.0001476114,0.0002630239,0.00008476297,0.0002119247,0.0002207874,0.0004844623],"category_scores_gemma":[0.0001862862,0.0001574436,0.00009105255,0.0002061198,0.0002089034,0.0002206281,0.0001614396,0.0004479479,0.0003914248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006311508,"about_ca_system_score_gemma":0.00009988884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007172421,"about_ca_topic_score_gemma":0.00003205028,"domain_scores_codex":[0.9981711,0.0005683712,0.0003563435,0.0003807555,0.0001959651,0.0003274959],"domain_scores_gemma":[0.9988966,0.0002323441,0.0001672519,0.0004870183,0.0001459641,0.0000708248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001999208,0.00002393743,0.0461761,0.00007047779,0.00007567916,0.0000277609,0.0002003961,0.00001740778,0.9452693,0.00003595495,0.0004372034,0.005666514],"study_design_scores_gemma":[0.001599235,0.0003873502,0.4166074,0.00007649111,0.00002146835,0.00008137702,0.0002386228,0.0002203788,0.5760542,0.00003407074,0.00444879,0.0002305404],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972095,0.0004985806,0.000033632,0.0001953202,0.0006524113,0.0008118493,0.00006035097,0.00006776369,0.0004706276],"genre_scores_gemma":[0.9941959,0.00003537472,0.00004642877,0.00008957266,0.000172834,0.00005223717,0.00002746597,0.00003116451,0.005349019],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3704313,"threshold_uncertainty_score":0.6420365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01363891685809151,"score_gpt":0.2556476637768472,"score_spread":0.2420087469187557,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}