{"id":"W2910527546","doi":"10.1158/1078-0432.ccr-18-3042","title":"Genomic Landscape of Pancreatic Adenocarcinoma in Younger versus Older Patients: Does Age Matter?","year":2019,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"National Cancer Institute","keywords":"Carcinogenesis; Pancreatic cancer; Transcriptome; Biology; Cohort; Oncology; Cancer; Adenocarcinoma; Gene; Somatic cell; Medicine; Population; Bioinformatics; Cancer research; Internal medicine; Genetics; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006454106,0.0001314062,0.0003923743,0.0006669864,0.0002480479,0.00070374,0.0002362484,0.0003299687,0.001973485],"category_scores_gemma":[0.002496182,0.00009721982,0.0003436582,0.001058721,0.0002386336,0.0005630897,0.000387837,0.0003447921,0.000311244],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002183836,"about_ca_system_score_gemma":0.0001800244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009841509,"about_ca_topic_score_gemma":0.001804919,"domain_scores_codex":[0.9995079,0.0001106584,0.00004694607,0.0002089882,0.00006058327,0.00006502637],"domain_scores_gemma":[0.9986516,0.0004071046,0.0005461335,0.000135888,0.00009178896,0.0001676358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000448483,0.00001357036,0.9874701,0.00004972874,0.0001438796,0.0001453613,0.000140967,0.00009680722,0.002823002,0.00009899459,0.0003063338,0.008262754],"study_design_scores_gemma":[0.000004848078,0.00007377545,0.9976575,0.00001392571,0.00005903122,0.0004099993,0.0001551733,0.000169738,0.0002257755,0.0002149103,0.001011156,0.000004041599],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949286,0.001947794,0.000324672,0.0002635827,0.00001224296,0.000007128992,0.001880697,0.000008398324,0.0006268939],"genre_scores_gemma":[0.9977913,0.0004592512,0.0001617041,0.00009645952,0.00002160957,0.000005654624,0.001320387,0.000008037223,0.0001356575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001973485,"threshold_uncertainty_score":0.00660193,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1247965173518892,"score_gpt":0.483262421585494,"score_spread":0.3584659042336048,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}