{"id":"W2910611768","doi":"10.1038/s41467-018-07962-9","title":"Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Engineering and Physical Sciences Research Council; Canadian Institutes of Health Research; National Institutes of Health; Eusko Jaurlaritza; Deutsche Forschungsgemeinschaft; Wolfson Foundation; Canada Research Chairs; Wellcome Trust","keywords":"STED microscopy; Epitope; Antibody; Protein subunit; Virology; Human immunodeficiency virus (HIV); Biophysics; Cell biology; Chemistry; Biology; Immunology; Biochemistry; Computer science; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001358423,0.0001760859,0.0002207583,0.000204093,0.0002092403,0.0003242225,0.0002664654,0.0004758661,0.0008456716],"category_scores_gemma":[0.0001967032,0.0001500869,0.0001736698,0.0001012745,0.0003271751,0.0003541101,0.0004122765,0.0006367639,0.0002709365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003357135,"about_ca_system_score_gemma":0.0001217684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003608699,"about_ca_topic_score_gemma":0.0003178195,"domain_scores_codex":[0.9999077,0.000009056645,0.000005556925,0.00003061067,0.00002525793,0.00002176876],"domain_scores_gemma":[0.9998966,0.0000405562,0.00001631704,0.0000189089,0.00001414554,0.00001342032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000289353,0.00001052748,0.0002839086,0.00003646086,0.000005708047,0.00006938403,0.0000433019,0.0003874966,0.9976982,0.0002822225,0.00005586799,0.001097995],"study_design_scores_gemma":[0.00001302437,0.00008711178,0.006789204,0.00001490574,0.00001152865,0.0003666277,0.0001017307,0.02052297,0.9705418,0.0003798342,0.001156165,0.00001496983],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987463,0.0004065319,0.01041471,0.0001021639,0.00001399682,0.00001335305,0.0002320309,0.00008445555,0.001269811],"genre_scores_gemma":[0.9913896,0.0004535733,0.006904009,0.00007466583,0.000007562933,0.00003472751,0.0002021917,0.00003021232,0.0009034928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008456716,"threshold_uncertainty_score":0.002829075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01546766946331126,"score_gpt":0.2940432038395935,"score_spread":0.2785755343762822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}