{"id":"W2910650156","doi":"10.1016/j.mad.2019.01.002","title":"Brain region-specific effects of long-term caloric restriction on redox balance of the aging rat","year":2019,"lang":"en","type":"article","venue":"Mechanisms of Ageing and Development","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Montreal Heart Institute; Université de Montréal; Institut National de la Recherche Scientifique; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research; Réseau québécois de recherche sur le vieillissement","keywords":"Hippocampus; Senescence; Caloric theory; Glial fibrillary acidic protein; Oxidative stress; Endocrinology; Internal medicine; Glutathione; Striatum; Antioxidant; Cerebellum; Aging brain; Biology; Oxidative phosphorylation; Neuroscience; Medicine; Biochemistry; Dopamine; Immunohistochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000166156,0.0007449893,0.0006120483,0.0006281338,0.0002221296,0.0003300832,0.000339862,0.0003205301,0.001483195],"category_scores_gemma":[0.0001445876,0.0002957501,0.0003730146,0.0002811004,0.0008463491,0.000398466,0.0003246001,0.0007478726,0.0001750642],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004431097,"about_ca_system_score_gemma":0.0004850428,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003964555,"about_ca_topic_score_gemma":0.008072237,"domain_scores_codex":[0.9999026,0.000007986371,0.000006152924,0.00003404561,0.00001210802,0.00003698951],"domain_scores_gemma":[0.9997167,0.00002815648,0.00008572486,0.00005174229,0.00002680195,0.00009088695],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.019721,0.0004230928,0.001564397,0.0001106068,0.0001047523,0.0001734226,0.00007690425,0.0001998642,0.9709861,0.0001690443,0.0001233196,0.006347509],"study_design_scores_gemma":[0.0005336975,0.007164884,0.1202308,0.00004201136,0.0005873378,0.0004632296,0.0004647527,0.0007689108,0.8669012,0.000683846,0.002091781,0.00006765393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981557,0.0009193207,0.0002391438,0.0000436269,0.0000216259,0.000004798654,0.000314375,0.00003748745,0.0002639375],"genre_scores_gemma":[0.9940753,0.001392037,0.0005379334,0.00008097203,0.0000119606,0.0000290872,0.0007002357,0.00004158482,0.003130899],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003964555,"threshold_uncertainty_score":0.007882953,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007977342667855448,"score_gpt":0.2090694859817437,"score_spread":0.2010921433138882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}