{"id":"W2910705150","doi":"10.1016/j.ejmech.2019.01.009","title":"Putative electron-affinic radiosensitizers and markers of hypoxic tissue: Synthesis and preliminary in vitro biological characterization of C3-amino-substituted benzotriazine dioxides (BTDOs)","year":2019,"lang":"en","type":"article","venue":"European Journal of Medicinal Chemistry","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; In vitro; In vivo; Biochemistry; Pharmacology; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002296794,0.0002953927,0.0001790136,0.0002324724,0.0001276932,0.0001229078,0.0002584013,0.0002400901,0.001148655],"category_scores_gemma":[0.0002393605,0.0001185377,0.000187273,0.0002248666,0.0001744693,0.0001524393,0.0001540994,0.0003051574,0.0002880814],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001792022,"about_ca_system_score_gemma":0.0002024371,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006522285,"about_ca_topic_score_gemma":0.0009026015,"domain_scores_codex":[0.9999082,0.0000263444,0.000007004566,0.00001708942,0.00001991873,0.00002143514],"domain_scores_gemma":[0.9998711,0.00003721331,0.00002911714,0.00001376815,0.00002592448,0.00002288966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001213273,0.00002083327,0.0001300491,0.00003979668,0.000004787812,0.0000474456,0.00002234049,0.0001820086,0.9974725,0.0001775787,0.0000257736,0.001755689],"study_design_scores_gemma":[0.000009840411,0.0004194371,0.0008747124,0.000002374796,0.00001046904,0.00008014045,0.000008077266,0.0002205529,0.997098,0.00002391533,0.00125015,0.000002451281],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.97858,0.002609104,0.01492254,0.00008622539,0.00002971943,0.0002010174,0.000675438,0.0001041693,0.002791853],"genre_scores_gemma":[0.9837189,0.001651888,0.01050191,0.00003348773,0.00001343971,0.00008969743,0.001052999,0.00002126273,0.002916406],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001148655,"threshold_uncertainty_score":0.003842592,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007039991667387906,"score_gpt":0.2184948570244195,"score_spread":0.2114548653570316,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}