{"id":"W2910810713","doi":"10.1039/c8mt00315g","title":"Disruption of selenium transport and function is a major contributor to mercury toxicity in zebrafish larvae","year":2019,"lang":"en","type":"article","venue":"Metallomics","topic":"Mercury impact and mitigation studies","field":"Environmental Science","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation; University of Saskatchewan","keywords":"Selenium; Mercury (programming language); Methylmercury; Chemistry; Selenoprotein; Toxicity; Environmental chemistry; Danio; Micronutrient; Zebrafish; Mercury poisoning; Antioxidant; Biochemistry; Glutathione peroxidase; Catalase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001062309,0.0004158795,0.0003094925,0.0003480951,0.0003244164,0.000233933,0.0002965788,0.0005480549,0.001767226],"category_scores_gemma":[0.0001602386,0.0002539048,0.0005421627,0.0001452728,0.0003328815,0.0002709466,0.000363999,0.0009768463,0.0003642137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009278061,"about_ca_system_score_gemma":0.0006214867,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009602149,"about_ca_topic_score_gemma":0.01503602,"domain_scores_codex":[0.9998719,0.000008840761,0.00001575841,0.00003323397,0.00004090649,0.00002939037],"domain_scores_gemma":[0.9998878,0.00001349395,0.00003637587,0.000009575053,0.00002446622,0.0000283515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008021542,0.00001035441,0.0004366635,0.00004294142,0.000004413128,0.0001070155,0.00002931581,0.00004671158,0.9985078,0.0000634615,0.00006738634,0.0006037087],"study_design_scores_gemma":[0.00002896761,0.0007661666,0.02793828,0.0000321709,0.00005872347,0.0003549125,0.0001628406,0.0008764094,0.9659159,0.0001435538,0.003697067,0.00002490547],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900837,0.002038904,0.002186215,0.0004967132,0.00005423787,0.00005733416,0.001440061,0.0001717686,0.00347107],"genre_scores_gemma":[0.9805223,0.001536072,0.002180962,0.0002546234,0.000008102927,0.0001425471,0.0009662457,0.00004921215,0.01434003],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009602149,"threshold_uncertainty_score":0.01909256,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009763850496044465,"score_gpt":0.2326315517030585,"score_spread":0.222867701207014,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}