{"id":"W2910843803","doi":"10.1136/annrheumdis-2018-eular.5296","title":"FRI0456 Predictors for disease worsening defined by organ failure in diffuse systemic sclerosis: a european scleroderma trials and research (EUSTAR) analysis","year":2018,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"St Joseph's Health Care; Western University","funders":"Medac; Actelion Pharmaceuticals; IC Design Education Center; Sanofi; Genentech; Bayer; Pfizer; Biogen; Bristol-Myers Squibb","keywords":"Medicine; Ejection fraction; Clinical trial; Internal medicine; Scleroderma (fungus); Population; Cardiology; Surrogate endpoint; Intensive care medicine; Heart failure; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005184789,0.001233372,0.002927621,0.00048256,0.0004555814,0.001891321,0.001008669,0.001750654,0.00431816],"category_scores_gemma":[0.006411802,0.0004758677,0.006479539,0.001108074,0.0006573679,0.00140974,0.0008268708,0.001973463,0.0006658114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004870774,"about_ca_system_score_gemma":0.0005640322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001179392,"about_ca_topic_score_gemma":0.002061421,"domain_scores_codex":[0.9973092,0.001508947,0.0002970217,0.0003879627,0.0001932342,0.0003037619],"domain_scores_gemma":[0.9956312,0.002102623,0.0009936078,0.0006043587,0.0002412013,0.0004269826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.6433429,0.0008030194,0.2127171,0.003231727,0.1030936,0.0004997338,0.0001284743,0.002181655,0.003746192,0.0006874048,0.004893344,0.02467481],"study_design_scores_gemma":[0.1060336,0.02745535,0.7125813,0.000512096,0.1364087,0.0009776856,0.0002906847,0.00310524,0.001457592,0.001534009,0.009454168,0.0001895344],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9605452,0.03152879,0.0006737724,0.0006899093,0.0003363786,0.0001197549,0.004352554,0.00005750903,0.001696075],"genre_scores_gemma":[0.9927522,0.002039742,0.0003852152,0.00039447,0.000330404,0.0001236094,0.003022645,0.00001983732,0.0009318663],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005184789,"threshold_uncertainty_score":0.0274201,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1402819412825582,"score_gpt":0.3609946364642505,"score_spread":0.2207126951816923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}