{"id":"W2910956408","doi":"10.18433/jpps29895","title":"Lifitegrast Ophthalmic Solution 5.0% for Treatment of Dry Eye Disease: Overview of Clinical Trial Program","year":2019,"lang":"en","type":"review","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Ocular Surface and Contact Lens","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo; University of Toronto","funders":"Shire","keywords":"Clinical trial; Medicine; Disease; Signs and symptoms; Drug; Pharmacology; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001280553,0.0006985608,0.001491066,0.002519161,0.0002588355,0.0008615531,0.0008820485,0.001035601,0.005754035],"category_scores_gemma":[0.001350941,0.0002761924,0.001508755,0.001591496,0.0002395356,0.0007681845,0.0004098723,0.001339435,0.001198045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005165078,"about_ca_system_score_gemma":0.001559072,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009434143,"about_ca_topic_score_gemma":0.00226,"domain_scores_codex":[0.9997017,0.00007251679,0.00007213054,0.00004014328,0.00009157605,0.00002201093],"domain_scores_gemma":[0.9993258,0.0003472122,0.0001106405,0.00001466674,0.0001612773,0.00004036958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0005740711,0.0002158669,0.0001443879,0.05812245,0.0003547901,0.0001086951,0.00006311793,0.0001944935,0.002075013,0.001494999,0.01481495,0.9218372],"study_design_scores_gemma":[0.0009550898,0.002289245,0.002563102,0.05600659,0.003068034,0.00188753,0.0001205977,0.0003596818,0.002437022,0.001684347,0.9285622,0.00006659877],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003877906,0.9977961,0.0001573115,0.0002728828,0.0001114079,0.0000866781,0.00007676728,0.00001314929,0.001097928],"genre_scores_gemma":[0.001765161,0.9965928,0.0004899008,0.0003338968,0.00009464614,0.0000843076,0.0001073778,0.000003552771,0.0005283529],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005754035,"threshold_uncertainty_score":0.01924914,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5820760614068166,"score_gpt":0.6285382946580867,"score_spread":0.04646223325127019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}