{"id":"W2911158691","doi":"10.1136/annrheumdis-2018-214930","title":"Altered DNA methylation in children born to mothers with rheumatoid arthritis during pregnancy","year":2019,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Pregnancy and Medication Impact","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; ReumaNederland; Arthritis Society; Erasmus Universiteit Rotterdam; ZonMw; European Commission; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Dutch Arthritis Society","keywords":"Medicine; DNA methylation; CpG site; Pregnancy; Methylation; Population; Rheumatoid arthritis; Confounding; Immunology; Internal medicine; Genetics; Biology; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003763562,0.0002519423,0.0004100429,0.0003653945,0.0002283157,0.0003481235,0.0002432744,0.0003363951,0.001644038],"category_scores_gemma":[0.001749219,0.0002343464,0.0003606729,0.0004561747,0.0002248486,0.0002164815,0.0002676987,0.0003335248,0.0001626103],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002624106,"about_ca_system_score_gemma":0.0002387891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004227587,"about_ca_topic_score_gemma":0.003433291,"domain_scores_codex":[0.9996479,0.00009171604,0.00002259703,0.0001179968,0.00005895689,0.0000608238],"domain_scores_gemma":[0.9993957,0.0001741393,0.0003099757,0.00003510785,0.00003970266,0.00004531429],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005061125,0.00001771029,0.9876424,0.00006759188,0.0001283405,0.00040204,0.0004132524,0.00004781522,0.004364511,0.00004180712,0.0001412609,0.006227182],"study_design_scores_gemma":[0.000007335339,0.0001169509,0.9974194,0.00002425682,0.00008276966,0.0009893967,0.0002049452,0.00006753814,0.0006887382,0.00004243137,0.0003521485,0.000004100118],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969841,0.001731411,0.0002408031,0.00007463461,0.00001168942,0.000004741588,0.0005589232,0.000007511027,0.0003862881],"genre_scores_gemma":[0.9978272,0.001121121,0.0003740918,0.00004839975,0.000009485726,0.00001199648,0.0003263684,0.000004881958,0.000276264],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004227587,"threshold_uncertainty_score":0.008405924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01546259548283343,"score_gpt":0.2774556132014548,"score_spread":0.2619930177186214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}