{"id":"W2911216374","doi":"10.1158/0008-5472.can-18-1602","title":"MNK1/NODAL Signaling Promotes Invasive Progression of Breast Ductal Carcinoma <i>In Situ</i>","year":2019,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Alberta; McGill University Health Centre; Northern Alberta Institute of Technology; McGill University; Jewish General Hospital","funders":"Canadian Cancer Society; Réseau de cancérologie Rossy; Canadian Institutes of Health Research; Cancer Research Society; National Cancer Institute; Government of Canada; Israel Cancer Research Fund","keywords":"Ductal carcinoma; Nodal signaling; Cancer research; NODAL; Tumor progression; Metastasis; Cancer; Breast cancer; Biology; Medicine; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007492653,0.0001311587,0.0003774025,0.0002937254,0.00004518834,0.00001747645,0.0001572984,0.00008452441,0.0008225035],"category_scores_gemma":[0.00006559442,0.0001060373,0.00009306138,0.000669065,0.0001580743,0.00009218862,0.0001351291,0.0004909888,0.00004768139],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002746606,"about_ca_system_score_gemma":0.001093075,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001126109,"about_ca_topic_score_gemma":0.000344103,"domain_scores_codex":[0.9978417,0.0001210615,0.0002795917,0.0004005966,0.0008272185,0.0005297962],"domain_scores_gemma":[0.9988769,0.0001234974,0.00006839006,0.0003441613,0.0004091548,0.0001779074],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007447313,0.0001653789,0.1342065,0.0008650206,0.00002906577,0.0000997704,0.0007026307,0.00000846357,0.8532014,0.00003366506,0.0003879838,0.009555344],"study_design_scores_gemma":[0.002379867,0.0005836841,0.03701573,0.001272927,0.0000237832,0.00008007254,0.0007485796,0.00001305607,0.9570058,0.000047362,0.0006985619,0.0001306063],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922043,0.002831227,0.000001667471,0.0007620453,0.0001429454,0.001141473,0.0000359777,0.00001360154,0.002866741],"genre_scores_gemma":[0.9984533,0.000225413,0.0001462507,0.00003997565,0.0002337017,0.0001218399,0.00001690955,0.00003207463,0.0007305568],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1038043,"threshold_uncertainty_score":0.9005837,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05585231429761935,"score_gpt":0.388667489394008,"score_spread":0.3328151750963887,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}