{"id":"W2911248302","doi":"10.3389/fimmu.2019.00154","title":"NKG2D and Its Ligand MULT1 Contribute to Disease Progression in a Mouse Model of Multiple Sclerosis","year":2019,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research; Multiple Sclerosis Society; Fonds de Recherche du Québec - Santé; Multiple Sclerosis Society of Canada; European Genomic Institute for Diabetes; Fondation pour l'Aide à la Recherche sur la Sclérose en Plaques","keywords":"NKG2D; Experimental autoimmune encephalomyelitis; Immunology; Cytotoxic T cell; CD8; Multiple sclerosis; Granzyme; Granzyme B; Biology; Immune system; Cell biology; Perforin; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002362639,0.001452875,0.0007679547,0.001019922,0.0003081908,0.0006016552,0.0003384021,0.001144929,0.002652994],"category_scores_gemma":[0.0001873167,0.0004170909,0.0005019689,0.000318113,0.0005162171,0.0005147306,0.0003989485,0.002368602,0.0008415302],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005140888,"about_ca_system_score_gemma":0.0003594059,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004634707,"about_ca_topic_score_gemma":0.0005872062,"domain_scores_codex":[0.9995382,0.00008517258,0.0000583076,0.00009951684,0.0001213392,0.00009757005],"domain_scores_gemma":[0.9995607,0.00002531221,0.0001363935,0.00003758109,0.00003467237,0.0002052918],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001543224,0.0005229171,0.0004808101,0.0001335361,0.0000222466,0.0002930255,0.00005816662,0.0001424746,0.9942927,0.0001791398,0.000164371,0.002167364],"study_design_scores_gemma":[0.0009103094,0.007668517,0.02193422,0.0001556524,0.0002546549,0.004153709,0.0001953563,0.004113488,0.9468082,0.0008108096,0.01295791,0.00003721601],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906501,0.00355762,0.001705788,0.0005696215,0.0001123065,0.0001046361,0.0008449483,0.0003057484,0.002149183],"genre_scores_gemma":[0.9822732,0.002567505,0.002728756,0.0002887204,0.00008040217,0.0003520363,0.001238339,0.0000748692,0.01039616],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002652994,"threshold_uncertainty_score":0.008875191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01304797935393494,"score_gpt":0.2224516028673116,"score_spread":0.2094036235133767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}