{"id":"W2911267336","doi":"10.1038/npg.els.0001893","title":"Li–Fraumeni Syndrome","year":2001,"lang":"en","type":"other","venue":"Encyclopedia of Life Sciences","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Li–Fraumeni syndrome; Germline; Germline mutation; Cancer; Cancer syndrome; Phenotype; Identification (biology); Genetics; Gene; Biology; Medicine; Mutation; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009099066,0.0009845537,0.00036046,0.001419169,0.0006143967,0.0003815997,0.0003628157,0.000812818,0.0300542],"category_scores_gemma":[0.0007032295,0.00009462525,0.0002588604,0.001055618,0.0003932798,0.0003590372,0.0004255015,0.0006322842,0.005451544],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002978625,"about_ca_system_score_gemma":0.0003102071,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001775268,"about_ca_topic_score_gemma":0.001604104,"domain_scores_codex":[0.9998925,0.00001092063,0.0000071339,0.00002278478,0.0000337038,0.00003296515],"domain_scores_gemma":[0.9998029,0.00004569074,0.00004337247,0.00001695768,0.00002546643,0.00006560449],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003033582,0.0001050392,0.03191968,0.0005374238,0.0001055524,0.6033244,0.0004863622,0.0005777823,0.02805311,0.02133763,0.07069269,0.2425571],"study_design_scores_gemma":[0.0000366157,0.00006621317,0.01273893,0.0001783597,0.00006236231,0.8258357,0.0001056215,0.0002334964,0.00489304,0.004902903,0.1509145,0.00003227225],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"review","genre_scores_codex":[0.4043627,0.07551743,0.01315978,0.01063657,0.002250901,0.0003098329,0.005495534,0.002834568,0.4854327],"genre_scores_gemma":[0.7708194,0.01449428,0.004548662,0.001664961,0.0004773117,0.00006917953,0.00195822,0.0001313136,0.2058367],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.0300542,"threshold_uncertainty_score":0.1005412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01531101631206551,"score_gpt":0.2682264078881013,"score_spread":0.2529153915760358,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}