{"id":"W2911284667","doi":"10.1002/chin.201216170","title":"ChemInform Abstract: Nicotinic Acids: Liver‐Targeted SCD Inhibitors with Preclinical Antidiabetic Efficacy.","year":2012,"lang":"en","type":"article","venue":"ChemInform","topic":"Calcium signaling and nucleotide metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Chemistry; Nicotinic agonist; Pharmacology; Biochemistry; Receptor; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001654523,0.0007865731,0.000324404,0.0005124992,0.0002269808,0.0003384116,0.0004611016,0.0005341002,0.007932483],"category_scores_gemma":[0.0000984927,0.0001827466,0.0001757253,0.0002705137,0.0001785825,0.0002069773,0.0001722778,0.0008019471,0.001811119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003551177,"about_ca_system_score_gemma":0.0005474269,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009388318,"about_ca_topic_score_gemma":0.001446946,"domain_scores_codex":[0.999952,0.000007399071,0.000002260716,0.000009153012,0.00001624041,0.00001306178],"domain_scores_gemma":[0.9999518,0.000004289636,0.000009810733,0.000002887152,0.000008193633,0.00002302937],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00847001,0.001615651,0.0006214146,0.0008234743,0.0001096801,0.0007060543,0.00005594084,0.002225038,0.8537318,0.003995841,0.01461908,0.1130259],"study_design_scores_gemma":[0.006376176,0.01408917,0.003779328,0.0001605976,0.0002676692,0.001554931,0.00004085902,0.002623371,0.8950736,0.0008825139,0.07510187,0.00004986972],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8354129,0.02616354,0.01285875,0.003587199,0.0009120422,0.001149156,0.01171132,0.001726051,0.106479],"genre_scores_gemma":[0.9302736,0.01544952,0.007553746,0.0007329361,0.0001624545,0.0002091804,0.006454355,0.00006243779,0.03910182],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007932483,"threshold_uncertainty_score":0.02653682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01626242565492669,"score_gpt":0.2578799686255599,"score_spread":0.2416175429706332,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}