{"id":"W2911347271","doi":"10.1016/j.atherosclerosis.2019.01.031","title":"Early rescue of lymphatic function limits atherosclerosis progression in Ldlr mice","year":2019,"lang":"en","type":"article","venue":"Atherosclerosis","topic":"Lymphatic System and Diseases","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Fondation Institut de Cardiologie de Montréal; Banting Research Foundation","keywords":"Lymphatic system; Lymphatic vessel; Medicine; LDL receptor; Lesion; Vascular endothelial growth factor C; Lymphangiogenesis; Downregulation and upregulation; Endothelial dysfunction; Internal medicine; Endocrinology; Pathology; Vascular endothelial growth factor A; Vascular endothelial growth factor; Cancer; Biology; Cholesterol; VEGF receptors; Lipoprotein; Metastasis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005693123,0.0007981939,0.0009340099,0.0009884316,0.000381563,0.001024909,0.0008874683,0.001494111,0.005818305],"category_scores_gemma":[0.0004521887,0.000488354,0.0008881206,0.0002808989,0.001066425,0.0007110633,0.0007359816,0.00361719,0.002506641],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004595095,"about_ca_system_score_gemma":0.0005170114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006598234,"about_ca_topic_score_gemma":0.0008499722,"domain_scores_codex":[0.9991585,0.0001355305,0.00009655347,0.0001569814,0.0001662252,0.0002860817],"domain_scores_gemma":[0.9985847,0.0001929704,0.0003727563,0.0002312784,0.0001003811,0.0005180104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000810013,0.0002315713,0.0001426186,0.00004711117,0.000009304135,0.0001525983,0.00005159958,0.0000815028,0.9961384,0.0004860921,0.0001415555,0.001707652],"study_design_scores_gemma":[0.0001675143,0.0006984152,0.001741022,0.00002286908,0.00003489942,0.000320507,0.00009588143,0.0009219116,0.9912601,0.000220541,0.004498003,0.00001830051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9791272,0.001914466,0.01089184,0.001122307,0.0003168912,0.0001157564,0.001637114,0.001263215,0.003611058],"genre_scores_gemma":[0.9713998,0.001088116,0.006231682,0.0003882065,0.0001221824,0.0001821687,0.001166868,0.0004925293,0.0189284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005818305,"threshold_uncertainty_score":0.01946419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01998020962901201,"score_gpt":0.2629564923447084,"score_spread":0.2429762827156964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}