{"id":"W2911469478","doi":"10.5772/intechopen.79697","title":"Adenoviral Vector-Based Vaccines and Gene Therapies: Current Status and Future Prospects","year":2019,"lang":"en","type":"book-chapter","venue":"IntechOpen eBooks","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Virology; Biology; Viral vector; Vector (molecular biology); Virus; Tropism; DNA vaccination; Immune system; Gene; Immunology; Immunization; Genetics; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006304735,0.0007792591,0.0009252231,0.001191361,0.0002828443,0.002314487,0.001000596,0.00123637,0.01260839],"category_scores_gemma":[0.0003380996,0.0004044717,0.0003777407,0.00237353,0.0006206589,0.002656842,0.0008586367,0.002352108,0.01008803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007290436,"about_ca_system_score_gemma":0.0006665377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005286529,"about_ca_topic_score_gemma":0.0007636604,"domain_scores_codex":[0.9997997,0.00002850651,0.00001382324,0.00003495193,0.0001023958,0.00002066724],"domain_scores_gemma":[0.9998511,0.00007449638,0.00001197848,0.000008177844,0.00002786526,0.00002640654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008378317,0.0001714854,0.00007622857,0.003485206,0.00001698889,0.00013224,0.0001314762,0.0005507207,0.01144724,0.02021297,0.0532392,0.9104524],"study_design_scores_gemma":[0.000009705338,0.00005391559,0.0001183026,0.0004630452,0.000007900565,0.0002910119,0.00002736638,0.0001378592,0.0009506925,0.004038898,0.9938922,0.0000091142],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000591482,0.9724602,0.002831078,0.001234527,0.001112194,0.00002378309,0.00006979894,0.0001246714,0.02155227],"genre_scores_gemma":[0.001909533,0.9548469,0.004937001,0.0008770238,0.000805748,0.00004518729,0.0001965938,0.00004578731,0.03633622],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01260839,"threshold_uncertainty_score":0.04217923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01577809927329542,"score_gpt":0.2796818494997074,"score_spread":0.263903750226412,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}