{"id":"W2911530632","doi":"10.1213/xaa.0000000000000581","title":"Malignant Hyperthermia in a Morbidly Obese Patient Depletes Community Dantrolene Resources","year":2017,"lang":"en","type":"article","venue":"A & A Case Reports","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal University Hospital","funders":"","keywords":"Dantrolene; Malignant hyperthermia; Medicine; Morbidly obese; Dosing; Anesthesia; Hypermetabolism; Presentation (obstetrics); Adipose tissue; Sugammadex; Intensive care medicine; Surgery; Obesity; Weight loss; Internal medicine; Intubation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003447076,0.0001180664,0.0001283923,0.00004184751,0.0003813464,0.00005362965,0.00006355579,0.0001078733,0.00001486027],"category_scores_gemma":[0.0002731515,0.0001035347,0.00006942351,0.00002735007,0.00005665548,0.000007340436,0.0001370093,0.0001095029,0.000002654935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001643522,"about_ca_system_score_gemma":0.00003325788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001489232,"about_ca_topic_score_gemma":0.001262845,"domain_scores_codex":[0.9991146,0.0001178807,0.0002689696,0.0002191618,0.0001082884,0.0001711091],"domain_scores_gemma":[0.998731,0.00001033393,0.0002492408,0.0008755078,0.00006591759,0.00006802702],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007513556,0.001124125,0.1531941,0.0001216632,0.0001884933,0.09079956,0.003724167,0.0008254273,0.6745309,0.00006788643,0.003241903,0.07143047],"study_design_scores_gemma":[0.003764117,0.002201982,0.1888608,0.0003963877,0.0001187068,0.1998018,0.004741516,0.003672588,0.3400463,0.0008556325,0.2537251,0.001815116],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977431,0.0002953017,0.00004926406,0.0001134561,0.0002539072,0.0001557214,0.000004397044,0.00001212546,0.001372711],"genre_scores_gemma":[0.9992527,0.00003220344,0.00007268065,0.0001469819,0.0001322078,0.00003163923,0.00003617156,0.00001579049,0.0002795881],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3344846,"threshold_uncertainty_score":0.4222022,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0186750466759663,"score_gpt":0.2564101683343055,"score_spread":0.2377351216583392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}