{"id":"W2911571221","doi":"10.1159/000495658","title":"Novel Complex Interactions between Mitochondrial and Nuclear DNA in Schizophrenia and Bipolar Disorder","year":2019,"lang":"en","type":"review","venue":"Complex Psychiatry","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Addiction and Mental Health","funders":"National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; Novo Nordisk; Assurex Health; University of Louisville; Ministry of Education, India; National Institute of Mental Health; Pfizer; Johns Hopkins University; Mayo Foundation for Medical Education and Research; University of Pennsylvania; Lundbeckfonden; H. Lundbeck A/S; Rush University; Wayne State University","keywords":"Mitochondrial DNA; Genetics; Bipolar disorder; Biology; Epistasis; Nuclear gene; Population stratification; Gene; Mitochondrion; Single-nucleotide polymorphism; Genotype; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003538744,0.0002841718,0.0004055593,0.0007653313,0.0001915421,0.0005943562,0.0001914362,0.0002995384,0.001499873],"category_scores_gemma":[0.0006738003,0.00011625,0.0003715593,0.001030827,0.0002802473,0.0002726502,0.0002758698,0.0002777107,0.0002056591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003714556,"about_ca_system_score_gemma":0.0005525703,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001741154,"about_ca_topic_score_gemma":0.004243509,"domain_scores_codex":[0.9997881,0.00005080701,0.0000330048,0.00005272634,0.00005867123,0.00001673395],"domain_scores_gemma":[0.9997105,0.0001032726,0.0001181659,0.000008061504,0.00003733394,0.00002266278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001531269,0.00006960405,0.09351532,0.03077263,0.004275971,0.01074216,0.00139051,0.0009201998,0.07873508,0.007674376,0.01442639,0.7559465],"study_design_scores_gemma":[0.0002445497,0.0009723413,0.4949093,0.008082597,0.009361905,0.04174771,0.00139101,0.0009814469,0.01144413,0.01721751,0.4134475,0.0002000442],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0330825,0.9616675,0.001240057,0.001121685,0.0003736792,0.00001138099,0.0005172743,0.00002763591,0.001958248],"genre_scores_gemma":[0.2428628,0.75033,0.002349912,0.0009129071,0.0005524068,0.00002375062,0.0009583974,0.00001639503,0.00199339],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001741154,"threshold_uncertainty_score":0.005017519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05900646145967196,"score_gpt":0.3379445287624866,"score_spread":0.2789380673028146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}