{"id":"W2911576860","doi":"10.3390/cancers11020167","title":"PI3k and Stat3: Oncogenes that are Required for Gap Junctional, Intercellular Communication","year":2019,"lang":"en","type":"review","venue":"Cancers","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Université de Sherbrooke; Queen's University; Memorial Sloan-Kettering Cancer Center; Canadian Breast Cancer Research Alliance; Université Laval","keywords":"PI3K/AKT/mTOR pathway; Proto-oncogene tyrosine-protein kinase Src; Cell biology; STAT3; Biology; Effector; Signal transduction; Intracellular; STAT protein; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001242471,0.0003929344,0.0001678183,0.000332065,0.0002865561,0.0004351033,0.0001855676,0.0002943119,0.002446398],"category_scores_gemma":[0.000112929,0.0001183232,0.0002232392,0.0003049012,0.0003131969,0.0002739425,0.0002263441,0.0005416282,0.0007369157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006241722,"about_ca_system_score_gemma":0.0006437384,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006583852,"about_ca_topic_score_gemma":0.001059076,"domain_scores_codex":[0.9998927,0.00001162677,0.000009934732,0.00002198987,0.00003379972,0.00002988174],"domain_scores_gemma":[0.9998884,0.000008278789,0.00004564425,0.000006046832,0.00001210945,0.00003945693],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005357143,0.00009792549,0.001554603,0.0003038462,0.0000228736,0.0005209685,0.00002654404,0.0002144764,0.9795232,0.003512004,0.0007712433,0.01291657],"study_design_scores_gemma":[0.0001581551,0.0007025817,0.04092189,0.00004272295,0.0001159274,0.003939258,0.00007478679,0.002499071,0.9055644,0.002455901,0.04350202,0.00002335002],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.8834122,0.07134565,0.01335901,0.002606166,0.0005956589,0.0001474907,0.003369447,0.000608224,0.02455615],"genre_scores_gemma":[0.975247,0.01082842,0.003311679,0.0002616433,0.00007552599,0.00005992396,0.002444643,0.00002373527,0.007747349],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.002446398,"threshold_uncertainty_score":0.008183956,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1384485495343205,"score_gpt":0.3595567642505922,"score_spread":0.2211082147162717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}