{"id":"W2911638808","doi":"10.1016/j.chemosphere.2019.01.141","title":"Exposure to dilute concentrations of bupropion affects zebrafish early life stages","year":2019,"lang":"en","type":"article","venue":"Chemosphere","topic":"Zebrafish Biomedical Research Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Fundação para a Ciência e a Tecnologia; Centro de Estudos Ambientais e Marinhos, Universidade de Aveiro; Ministério da Educação; Ministério da Ciência, Tecnologia e Ensino Superior; Associação Médica Brasileira; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Diagnostic Services Manitoba; ASCRS Research Foundation","keywords":"Zebrafish; Danio; Aché; Acetylcholinesterase; Bupropion; Catalase; Chemistry; Lactate dehydrogenase; Toxicity; Glutathione; Hatching; Acute toxicity; Reuptake; Pharmacology; Toxicology; Internal medicine; Antioxidant; Biology; Enzyme; Biochemistry; Serotonin; Animal science; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000108308,0.0004095475,0.0002861889,0.0002241536,0.0001968506,0.0002936532,0.0002523159,0.0006622851,0.003510142],"category_scores_gemma":[0.0001828543,0.0001829778,0.0003064286,0.0001268656,0.0003461366,0.0002507711,0.0002586934,0.0006660653,0.0003042627],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004819999,"about_ca_system_score_gemma":0.0003236324,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00302513,"about_ca_topic_score_gemma":0.005290046,"domain_scores_codex":[0.99983,0.0000156017,0.00001360438,0.000034884,0.00005007478,0.00005582294],"domain_scores_gemma":[0.9998449,0.00003364573,0.000044773,0.00001111553,0.00002976841,0.00003569782],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001818546,0.00001590312,0.0002345858,0.00001845375,0.000003468997,0.00004409978,0.00001924465,0.00002074374,0.9989409,0.00002198464,0.00003539039,0.000463422],"study_design_scores_gemma":[0.00001369747,0.0007739177,0.01226256,0.000006858717,0.00002072685,0.000077096,0.00009148786,0.0001646548,0.9857401,0.00003218053,0.0008090845,0.000007601435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942491,0.000754154,0.0009502619,0.0002916636,0.00006335943,0.00005539072,0.0007948247,0.00006293655,0.002778181],"genre_scores_gemma":[0.9876103,0.000648018,0.001097247,0.000198137,0.00001863222,0.00007649978,0.0006318999,0.00001979554,0.009699532],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003510142,"threshold_uncertainty_score":0.01174259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007212387783944191,"score_gpt":0.2556402155798487,"score_spread":0.2484278277959045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}