{"id":"W2911788128","doi":"10.1113/jp277157","title":"Parkin overexpression protects from ageing‐related loss of muscle mass and strength","year":2019,"lang":"en","type":"article","venue":"The Journal of Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":119,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Institut Universitaire de Gériatrie de Montréal; Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Parkin; Mitophagy; Ageing; Sarcopenia; Mitochondrion; Skeletal muscle; PINK1; Endocrinology; Internal medicine; Biology; Cell biology; Autophagy; Chemistry; Medicine; Apoptosis; Biochemistry; Parkinson's disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000188094,0.0004725838,0.0004149517,0.0003253679,0.0001460663,0.0002813479,0.0002101172,0.0003660355,0.001336148],"category_scores_gemma":[0.00008675921,0.0002066296,0.0002985559,0.0001314854,0.0002926602,0.0003209016,0.0002224821,0.0006336914,0.0002806768],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002108551,"about_ca_system_score_gemma":0.0001802888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003913019,"about_ca_topic_score_gemma":0.0005583714,"domain_scores_codex":[0.9998987,0.000008953646,0.00001664757,0.00003368556,0.00001714495,0.00002484052],"domain_scores_gemma":[0.9997141,0.00002426411,0.0001113676,0.00002602558,0.0000255919,0.00009866939],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004575396,0.00007104413,0.0002507361,0.00005206123,0.000008656019,0.00003410692,0.0000118335,0.00003350281,0.9979361,0.00002246777,0.0000300356,0.001091899],"study_design_scores_gemma":[0.0001426349,0.003615499,0.02154942,0.0000384903,0.00006938761,0.0003309117,0.00008467314,0.0007218936,0.9710714,0.00008097718,0.002283291,0.00001140676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962566,0.001846185,0.0009383683,0.00008205108,0.00003757888,0.00001818957,0.0003161664,0.00009928684,0.0004056994],"genre_scores_gemma":[0.9917606,0.001547383,0.001309562,0.00008236124,0.00002208639,0.00005851978,0.0007137121,0.00003782521,0.004467967],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001336148,"threshold_uncertainty_score":0.004469872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007392048258940284,"score_gpt":0.247080589534867,"score_spread":0.2396885412759267,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}