{"id":"W2911788128","doi":"10.1113/jp277157","title":"Parkin overexpression protects from ageing‐related loss of muscle mass and strength","year":2019,"lang":"en","type":"article","venue":"The Journal of Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":119,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Institut Universitaire de Gériatrie de Montréal; Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Parkin; Mitophagy; Ageing; Sarcopenia; Mitochondrion; Skeletal muscle; PINK1; Endocrinology; Internal medicine; Biology; Cell biology; Autophagy; Chemistry; Medicine; Apoptosis; Biochemistry; Parkinson's disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001438859,0.00007625527,0.0002867581,0.00003461805,0.00002127953,0.000001489269,0.00009349615,0.0000696007,0.0004484208],"category_scores_gemma":[0.00002641431,0.00004136292,0.00006524214,0.0000457301,0.00008202136,0.00004277295,0.00002614059,0.0002234441,0.000008393373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009104636,"about_ca_system_score_gemma":0.00004017852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002188963,"about_ca_topic_score_gemma":1.871472e-7,"domain_scores_codex":[0.99934,0.0001410885,0.0002399896,0.00006654968,0.0001144953,0.00009787618],"domain_scores_gemma":[0.9992335,0.0001486087,0.0003351667,0.0001765072,0.00005409979,0.00005205704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0009175043,0.00007972605,0.0005728438,0.00003046294,0.0001651693,0.00001355057,0.0003978478,0.00002987517,0.9966065,0.00003387927,0.00007733255,0.001075283],"study_design_scores_gemma":[0.004198147,0.001312261,0.5957624,0.0005396169,0.0001626907,0.00003914453,0.000237883,0.0003077001,0.3820073,0.01496152,0.000386256,0.00008499805],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983865,0.001076715,0.000008861156,0.0001435268,0.00009037404,0.0001448406,0.000005058737,0.000004441803,0.0001396646],"genre_scores_gemma":[0.9993618,0.0002820013,0.00006634001,0.0001117165,0.0001007131,6.181883e-7,0.000002486197,0.000008771036,0.00006559573],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6145992,"threshold_uncertainty_score":0.4909893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007392048258940284,"score_gpt":0.247080589534867,"score_spread":0.2396885412759267,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}