{"id":"W2912017753","doi":"10.1002/art.40803","title":"Tofacitinib in Combination With Methotrexate in Patients With Rheumatoid Arthritis: Clinical Efficacy, Radiographic, and Safety Outcomes From a Twenty‐Four–Month, Phase <scp>III</scp> Study","year":2019,"lang":"en","type":"article","venue":"Arthritis & Rheumatology","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"Pfizer","keywords":"Tofacitinib; Rheumatoid arthritis; Methotrexate; Medicine; Radiography; Internal medicine; Phases of clinical research; Dermatology; Surgery; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00358666,0.0009352647,0.00187181,0.0003987244,0.0004407844,0.0009781315,0.0005505169,0.0009195326,0.00206966],"category_scores_gemma":[0.002162353,0.0003907245,0.00226558,0.0005231829,0.0004034858,0.0005270713,0.0003773182,0.001527319,0.0004634996],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005178326,"about_ca_system_score_gemma":0.001017217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005701206,"about_ca_topic_score_gemma":0.001116743,"domain_scores_codex":[0.9988012,0.0006986097,0.0001056098,0.0001231328,0.0001723583,0.00009899023],"domain_scores_gemma":[0.9978986,0.0003956697,0.0008198243,0.0001412959,0.0001716987,0.000572943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8526591,0.01405004,0.04437753,0.0009705403,0.009713486,0.0002633949,0.0002018514,0.001163193,0.007954502,0.00008010692,0.002158477,0.06640773],"study_design_scores_gemma":[0.6614808,0.1984913,0.1286701,0.0001169598,0.005441973,0.0004334472,0.00007406763,0.001551779,0.001028476,0.0001298904,0.002523317,0.00005784125],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936929,0.003875339,0.0002193225,0.0002642977,0.00004853843,0.0004160785,0.0007178378,0.00002054281,0.00074516],"genre_scores_gemma":[0.9937304,0.001980946,0.0006199192,0.0004560354,0.0002526194,0.0006357881,0.001663869,0.000007774194,0.0006526203],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00358666,"threshold_uncertainty_score":0.01896834,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01405376799443348,"score_gpt":0.2890747562866647,"score_spread":0.2750209882922312,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}