{"id":"W2912046117","doi":"10.1002/rcm.8401","title":"Comparison of data‐acquisition methods for the identification and quantification of histone post‐translational modifications on a Q Exactive HF hybrid quadrupole Orbitrap mass spectrometer","year":2019,"lang":"en","type":"article","venue":"Rapid Communications in Mass Spectrometry","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Wellcome Trust; Wellcome","keywords":"Orbitrap; Mass spectrometry; Triple quadrupole mass spectrometer; Quadrupole; Chemistry; Quadrupole mass analyzer; Chromatography; Analytical Chemistry (journal); Spectrometer; Selected reaction monitoring; Physics; Tandem mass spectrometry; Optics; Atomic physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007328562,0.0009724171,0.0006098508,0.001745621,0.0005062862,0.0009495626,0.001401905,0.001058689,0.00123951],"category_scores_gemma":[0.007811194,0.0004735168,0.0006593984,0.001236377,0.0003997539,0.0009676311,0.0009253809,0.0008936968,0.0005923431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006711195,"about_ca_system_score_gemma":0.0006671943,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001297823,"about_ca_topic_score_gemma":0.001832357,"domain_scores_codex":[0.9957864,0.0009725338,0.0005826742,0.0006772932,0.001782203,0.0001989373],"domain_scores_gemma":[0.9938408,0.002747159,0.0007786656,0.0004417257,0.001977077,0.0002145658],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004469463,0.0003962193,0.009680692,0.0007896303,0.0004351727,0.0001000397,0.0001990432,0.001493013,0.9144263,0.0003368591,0.0007406768,0.0669329],"study_design_scores_gemma":[0.000257297,0.00270138,0.05921465,0.0001141882,0.0004704621,0.001090139,0.000198443,0.03146505,0.8975957,0.0004533485,0.006208459,0.0002308064],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7823412,0.008198629,0.1998729,0.0006942566,0.0002834724,0.0008905276,0.003341745,0.001679645,0.002697623],"genre_scores_gemma":[0.5103739,0.003709992,0.4771647,0.000579924,0.00007496516,0.001556618,0.004602123,0.0005072982,0.00143048],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007328562,"threshold_uncertainty_score":0.03875756,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05247596843254152,"score_gpt":0.4054873981824484,"score_spread":0.3530114297499069,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}