{"id":"W2912076336","doi":"10.1523/eneuro.0019-19.2019","title":"Developmental Axon Degeneration Requires TRPV1-Dependent Ca<sup>2+</sup>Influx","year":2019,"lang":"en","type":"article","venue":"eNeuro","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Okanagan University College; McGill University; University of British Columbia, Okanagan Campus; University of British Columbia; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research","keywords":"TRPV1; Axon; Transient receptor potential channel; Cell biology; Chemistry; Neuroscience; Nerve growth factor; Dorsal root ganglion; Protein kinase C; Reactive oxygen species; Biology; Signal transduction; Sensory system; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001609954,0.0002250536,0.0002858838,0.0002158838,0.0001877999,0.0004001186,0.0002328852,0.000325348,0.0009589704],"category_scores_gemma":[0.0002053851,0.0001495635,0.0002544646,0.0001214893,0.0003841152,0.0004392096,0.0003017466,0.0005151503,0.0003429557],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005079274,"about_ca_system_score_gemma":0.0003867567,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007267818,"about_ca_topic_score_gemma":0.001155497,"domain_scores_codex":[0.9997978,0.00001771513,0.00002079823,0.00003633258,0.00006107258,0.00006637438],"domain_scores_gemma":[0.9998318,0.0000226577,0.00006966237,0.00001320351,0.00002465795,0.00003803142],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006576734,0.000007967732,0.0002810389,0.0000317042,0.000001962151,0.00008774303,0.00001435678,0.00003222915,0.9989304,0.00009931614,0.00001369641,0.0004339149],"study_design_scores_gemma":[0.00001959547,0.0002398331,0.03803713,0.00001907274,0.00001752281,0.000806717,0.000103902,0.0009384176,0.9579304,0.0002828955,0.001593489,0.00001099139],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937803,0.001668942,0.002754632,0.0001181341,0.00002894283,0.00001665436,0.0002313146,0.00006885808,0.001332125],"genre_scores_gemma":[0.9962384,0.0007608411,0.001214363,0.00004288965,0.000006332545,0.00002429708,0.0002370862,0.00001085715,0.001464899],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009589704,"threshold_uncertainty_score":0.003685236,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02649466555889136,"score_gpt":0.2433660439386454,"score_spread":0.2168713783797541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}