{"id":"W2912076336","doi":"10.1523/eneuro.0019-19.2019","title":"Developmental Axon Degeneration Requires TRPV1-Dependent Ca<sup>2+</sup>Influx","year":2019,"lang":"en","type":"article","venue":"eNeuro","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Okanagan University College; McGill University; University of British Columbia, Okanagan Campus; University of British Columbia; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research","keywords":"TRPV1; Axon; Transient receptor potential channel; Cell biology; Chemistry; Neuroscience; Nerve growth factor; Dorsal root ganglion; Protein kinase C; Reactive oxygen species; Biology; Signal transduction; Sensory system; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000117296,0.0001816037,0.0001462273,0.00009324733,0.0001787437,0.00008184752,0.000243696,0.00008178604,0.001092719],"category_scores_gemma":[0.0001410185,0.0001552423,0.00006436566,0.0001659997,0.00003863878,0.0002635226,0.000108231,0.0001559011,0.002529079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006721656,"about_ca_system_score_gemma":0.00006983094,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002023962,"about_ca_topic_score_gemma":0.000004496136,"domain_scores_codex":[0.9984004,0.0001162056,0.0002489091,0.0005004512,0.0004093621,0.000324615],"domain_scores_gemma":[0.9995915,0.00008966712,0.00006702363,0.0001288571,0.00002389767,0.0000991006],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002625799,0.00006072138,0.0002996958,0.00001352586,0.000002625072,0.0000248141,0.0008531551,0.008533397,0.9840637,0.0003812695,0.003976326,0.001764462],"study_design_scores_gemma":[0.0003840968,0.0000866535,0.0001201087,0.00001135631,0.000003427705,0.0000476004,0.0001296353,0.004843998,0.9648729,0.0000448059,0.02923632,0.0002191159],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903079,0.00001958383,0.00005583877,0.0003506855,0.001204666,0.0002677118,0.00001163024,0.0001057889,0.007676203],"genre_scores_gemma":[0.9854899,0.00004386652,0.0001213096,0.001536836,0.0002730278,0.0000180428,0.000007790283,0.00003165945,0.01247756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02525999,"threshold_uncertainty_score":0.9998204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02649466555889136,"score_gpt":0.2433660439386454,"score_spread":0.2168713783797541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}