{"id":"W2912081141","doi":"10.1128/jvi.02299-18","title":"Cytoplasm and Beyond: Dynamic Innate Immune Sensing of Influenza A Virus by RIG-I","year":2019,"lang":"en","type":"review","venue":"Journal of Virology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada; Public Health Agency of Canada","keywords":"Biology; Innate immune system; RIG-I; Cytoplasm; Influenza A virus; Virology; Cell biology; Virus; Viral replication; MDA5; Immune system; RNA; Gene; Genetics; RNA interference","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007467576,0.0004604619,0.003250164,0.000667682,0.00006843179,0.00001296768,0.0004103635,0.001167584,0.0001846387],"category_scores_gemma":[0.0002063058,0.0003440128,0.0006319793,0.000130284,0.0004790221,0.0001039727,0.0002236357,0.00155282,0.0001701868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008714195,"about_ca_system_score_gemma":0.0003151225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002357771,"about_ca_topic_score_gemma":0.000003196153,"domain_scores_codex":[0.9962326,0.001155114,0.001884126,0.0002565692,0.00005561303,0.0004160162],"domain_scores_gemma":[0.9963065,0.0006825528,0.002464242,0.0003562349,0.0001594299,0.0000310757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001555221,0.0001929624,0.000006034223,0.003281987,0.003267023,0.00007958699,0.0002996353,6.69247e-7,0.2814195,0.00008285008,0.00252536,0.7072892],"study_design_scores_gemma":[0.001382087,0.001590214,0.00002505365,0.00199919,0.00114271,0.007688505,0.00004177709,0.000001445946,0.002606821,0.00003168745,0.9832065,0.0002840245],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02392035,0.9739872,0.00003716653,0.00004688052,0.001501283,0.0002233617,0.0001103015,0.000008593075,0.0001648723],"genre_scores_gemma":[0.002990131,0.9956441,0.00005368928,0.000210091,0.00002236264,0.000001342358,0.00003113769,0.00005098803,0.000996192],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9806811,"threshold_uncertainty_score":0.9999012,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01930261138965727,"score_gpt":0.3142853340781944,"score_spread":0.2949827226885371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}