{"id":"W2912214821","doi":"10.1016/j.bbmt.2019.02.011","title":"Nonmyeloablative Matched Sibling Donor Hematopoietic Cell Transplantation in Children and Adolescents with Sickle Cell Disease","year":2019,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":false,"ca_institutions":"Stollery Children's Hospital; Alberta Children's Hospital; University of Alberta; University of Calgary","funders":"University of Illinois at Chicago; Health Research Board","keywords":"Medicine; Alemtuzumab; Hematopoietic stem cell transplantation; Total body irradiation; Transplantation; Regimen; Granulocyte colony-stimulating factor; Sibling; Hemoglobinopathy; Internal medicine; Disease; Pediatrics; Surgery; Immunology; Cyclophosphamide; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007486575,0.0001381633,0.0002474248,0.000132465,0.00002835444,0.00000463233,0.00002658015,0.0001218048,0.000009728565],"category_scores_gemma":[0.000001206649,0.0001081375,0.0000272634,0.00009100517,0.00008760632,0.00006652116,0.000003064315,0.0001197007,0.000002355871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003831216,"about_ca_system_score_gemma":0.00003757429,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008268769,"about_ca_topic_score_gemma":0.00001964341,"domain_scores_codex":[0.9992738,0.00004139888,0.0002107926,0.0002483967,0.0000675046,0.0001580768],"domain_scores_gemma":[0.9997159,0.00002247072,0.00007824689,0.00007152583,0.00002325629,0.00008856312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00142192,0.0002185818,0.88936,0.001868383,0.00003258312,0.00001796587,0.001812586,0.00002679903,0.1049895,0.00002188204,5.928395e-7,0.000229223],"study_design_scores_gemma":[0.01305226,0.0006518844,0.9432551,0.0009421023,0.000856431,0.000117053,0.0004228359,0.00007653004,0.04032384,0.00008740032,0.000001603442,0.0002129078],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976588,0.001190382,0.0001672142,0.0001013917,0.00002277818,0.0005906652,0.00005267941,0.00001606946,0.0001999765],"genre_scores_gemma":[0.9945382,0.004871163,0.0002259906,0.00005895267,0.000008196235,0.000007296998,0.0002486774,0.00001218445,0.0000293804],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06466564,"threshold_uncertainty_score":0.4409719,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002966254749711528,"score_gpt":0.194595337015095,"score_spread":0.1916290822653835,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}