{"id":"W2912258761","doi":"10.1186/s13046-018-1016-8","title":"N-acetylcysteine decreases malignant characteristics of glioblastoma cells by inhibiting Notch2 signaling","year":2019,"lang":"en","type":"article","venue":"Journal of Experimental & Clinical Cancer Research","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"China Postdoctoral Science Foundation; National Natural Science Foundation of China; Wenzhou University; Wenzhou Medical University","keywords":"Acetylcysteine; Glioblastoma; Cancer research; Apoptosis; Chemistry; Internal medicine; Medicine; Oncology; Antioxidant; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000105067,0.0003180948,0.0002856966,0.0002693348,0.0001135951,0.0001224441,0.0001864596,0.0001858362,0.0007001511],"category_scores_gemma":[0.00008802162,0.00006849109,0.0002440582,0.0001519022,0.0001407609,0.0001385393,0.0001353169,0.0003413552,0.0001144657],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002258104,"about_ca_system_score_gemma":0.0002916188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007583213,"about_ca_topic_score_gemma":0.001676246,"domain_scores_codex":[0.9999194,0.00001287123,0.00001185341,0.00001157671,0.00002464413,0.00001961659],"domain_scores_gemma":[0.9999585,0.000003761855,0.00001094903,0.000004236471,0.00001073674,0.00001184645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005939063,0.0001753535,0.000611752,0.0002031158,0.00003866952,0.00007405663,0.00002143753,0.0001013837,0.9911292,0.00007570236,0.0002153635,0.006760035],"study_design_scores_gemma":[0.0000790033,0.001636822,0.006315228,0.00001948083,0.0000824192,0.0002616408,0.00003539073,0.0009944194,0.9868156,0.00005798877,0.003694761,0.000007032045],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895176,0.007427566,0.001056547,0.000125432,0.00006362841,0.00004150326,0.0002398995,0.0001026587,0.00142522],"genre_scores_gemma":[0.9943216,0.002886845,0.001083748,0.00008017793,0.0000147813,0.00003620809,0.0003201162,0.000009352894,0.001247022],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007583213,"threshold_uncertainty_score":0.002342224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05869764032663751,"score_gpt":0.4343285344081895,"score_spread":0.375630894081552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}