{"id":"W2912287004","doi":"10.1155/2019/4569826","title":"Systemic Sclerosis Pathogenesis and Emerging Therapies, beyond the Fibroblast","year":2019,"lang":"en","type":"review","venue":"BioMed Research International","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Pathogenesis; Disease; Medicine; Multiple sclerosis; Mechanism (biology); Immunology; Fibrosis; Scleroderma (fungus); Immune system; Bioinformatics; Inflammation; Clinical trial; Autoimmune disease; Pathology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006047889,0.0005686043,0.0009606252,0.001938137,0.0002972696,0.001071292,0.0005606408,0.001086259,0.003368791],"category_scores_gemma":[0.0008105125,0.0001457334,0.0003651997,0.001551977,0.0005070606,0.001507431,0.0005586924,0.001929032,0.001360296],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005451036,"about_ca_system_score_gemma":0.001201234,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006424329,"about_ca_topic_score_gemma":0.001480306,"domain_scores_codex":[0.9998047,0.00004174193,0.00002883768,0.00003146001,0.00007358188,0.00001973378],"domain_scores_gemma":[0.9995677,0.0002489783,0.0000415921,0.00001341887,0.0000961095,0.00003220358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006355441,0.00006463644,0.0001463355,0.01440882,0.00005956031,0.000243158,0.00009547291,0.0002853926,0.001529191,0.007730598,0.03887524,0.9364981],"study_design_scores_gemma":[0.00001087087,0.0000676002,0.0004177817,0.004877988,0.00005874439,0.001290972,0.00007227607,0.00006691191,0.0002435122,0.003019161,0.9898642,0.00000994923],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005407815,0.9986112,0.00005797784,0.0003887181,0.0002647718,0.000001480419,0.000006086648,0.000003311065,0.0006124686],"genre_scores_gemma":[0.0005199639,0.9981753,0.0001332367,0.000330343,0.0003722671,0.000002936417,0.00001249367,9.472448e-7,0.0004525239],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003368791,"threshold_uncertainty_score":0.01126975,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2134986940994304,"score_gpt":0.4217504100768802,"score_spread":0.2082517159774499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}