{"id":"W2912287004","doi":"10.1155/2019/4569826","title":"Systemic Sclerosis Pathogenesis and Emerging Therapies, beyond the Fibroblast","year":2019,"lang":"en","type":"review","venue":"BioMed Research International","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Pathogenesis; Disease; Medicine; Multiple sclerosis; Mechanism (biology); Immunology; Fibrosis; Scleroderma (fungus); Immune system; Bioinformatics; Inflammation; Clinical trial; Autoimmune disease; Pathology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001608697,0.0003442704,0.0009689685,0.000867195,0.0002530338,0.0002017703,0.000599588,0.0003864325,0.0003457807],"category_scores_gemma":[0.0002794247,0.0001840548,0.0004720904,0.0007081294,0.0004194214,0.00006648705,0.0003620189,0.0006361191,0.0003655279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003756006,"about_ca_system_score_gemma":0.0005810328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000374743,"about_ca_topic_score_gemma":8.062442e-7,"domain_scores_codex":[0.9960514,0.0005833316,0.0007079838,0.0006256026,0.00155627,0.0004754257],"domain_scores_gemma":[0.9976498,0.0007958106,0.0002550605,0.0006072682,0.000455456,0.0002366446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003787231,0.00008973295,0.00006688488,0.01050074,0.001580386,0.00002123842,0.00015168,1.51205e-7,0.0006580511,0.0003623506,0.01960601,0.9669249],"study_design_scores_gemma":[0.0005548706,0.00008511169,0.00021733,0.09519463,0.0004169313,0.0004402294,0.0004043035,0.00003655477,0.000005874092,0.00001440259,0.9024157,0.0002140652],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004033335,0.9942752,0.0000049411,0.0008202998,0.001411229,0.001678431,0.0003005598,0.00004505607,0.001060932],"genre_scores_gemma":[0.001141588,0.9924164,0.00003022208,0.00005529831,0.001216356,0.0003521922,0.0003311833,0.00007884707,0.004377885],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9667108,"threshold_uncertainty_score":0.7505538,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2134986940994304,"score_gpt":0.4217504100768802,"score_spread":0.2082517159774499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}