{"id":"W2912331195","doi":"10.1016/j.actbio.2019.01.050","title":"Intervertebral disc regeneration with an adipose mesenchymal stem cell-derived tissue-engineered construct in a rat nucleotomy model","year":2019,"lang":"en","type":"article","venue":"Acta Biomaterialia","topic":"Spine and Intervertebral Disc Pathology","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":false,"ca_institutions":"Alberta Bone and Joint Health Institute; University of Calgary","funders":"Nakatomi Foundation","keywords":"Mesenchymal stem cell; Intervertebral disc; TEC; Regeneration (biology); Adipose tissue; Stem cell; Medicine; Biomedical engineering; Tissue engineering; Scaffold; Anatomy; Pathology; Biology; Cell biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001063776,0.0002961066,0.0005097683,0.0001906635,0.00003035423,0.00005536328,0.0001678382,0.0001855432,0.0007617345],"category_scores_gemma":[0.000005381896,0.0002233115,0.00006346445,0.000164199,0.00007943153,0.0004845011,0.00006657625,0.00009599013,0.0001344276],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007312075,"about_ca_system_score_gemma":0.0000820257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001147742,"about_ca_topic_score_gemma":0.00005850228,"domain_scores_codex":[0.9984685,0.00009145339,0.0004266002,0.0004730591,0.0001739701,0.0003663921],"domain_scores_gemma":[0.9991795,0.000002309416,0.0001111266,0.0004894499,0.00006526457,0.0001523724],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003514415,0.0001601067,0.0009765055,0.0001236802,0.00003346131,0.00008882531,0.0005668825,0.00001684836,0.9961796,0.0001322638,0.0009791523,0.0003912754],"study_design_scores_gemma":[0.004768748,0.002269918,0.008205956,0.0001929855,0.00007388809,0.0002187463,0.0003009525,0.02462175,0.9588672,0.00002249396,0.0001010473,0.0003562935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971892,0.00004299352,0.0003066724,0.0003224445,0.0007691841,0.0007045173,0.00004134215,0.0001154917,0.0005081622],"genre_scores_gemma":[0.9954849,0.000006468818,0.002510624,0.0002114942,0.00009791967,0.00004137947,0.0002987247,0.00005217624,0.001296269],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03731234,"threshold_uncertainty_score":0.9106379,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01484875336262993,"score_gpt":0.2553132872259388,"score_spread":0.2404645338633089,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}