{"id":"W2912334457","doi":"10.3389/fimmu.2019.00081","title":"HIV Impacts CD34+ Progenitors Involved in T-Cell Differentiation During Coculture With Mouse Stromal OP9-DL1 Cells","year":2019,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Infection and Immunity; Medical Research Council; Center for AIDS Research, University of Washington; University of New South Wales; Kumamoto University; Ministry of Education, Culture, Sports, Science and Technology; National Health and Medical Research Council; Japan Agency for Medical Research and Development","keywords":"CD34; Progenitor cell; Haematopoiesis; Biology; Stromal cell; CXCR4; Lymphopoiesis; Stem cell; Immunology; Cell biology; T cell; Cancer research; Immune system; Chemokine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001566991,0.0002496775,0.000202993,0.0002325116,0.0001543706,0.0003269996,0.0001809568,0.0001683069,0.001156241],"category_scores_gemma":[0.00007796533,0.0001231747,0.0001740658,0.0001683353,0.0001009989,0.0001265741,0.000230494,0.0006890922,0.0004467006],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001562713,"about_ca_system_score_gemma":0.0001526701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009626132,"about_ca_topic_score_gemma":0.001159868,"domain_scores_codex":[0.9998186,0.00003356086,0.00001664225,0.00003095096,0.00004791475,0.00005227432],"domain_scores_gemma":[0.9999205,0.00001727487,0.00001438054,0.00001046769,0.00001036606,0.00002701241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001682216,0.00005037122,0.0004677512,0.00003835345,0.000003621484,0.0001044501,0.00004522616,0.00007869783,0.9969006,0.0001753714,0.00004290392,0.001924478],"study_design_scores_gemma":[0.00001125465,0.0002391502,0.003473051,0.0000104784,0.00001439565,0.0002209983,0.00004051215,0.001248279,0.9922665,0.00005583867,0.002416901,0.000002629019],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922929,0.001931455,0.002718695,0.00005288453,0.00002575195,0.00003184105,0.0004087315,0.00005282294,0.002484806],"genre_scores_gemma":[0.9925282,0.00107495,0.003146127,0.00003883305,0.00001187832,0.00003793067,0.0006897971,0.00001944253,0.002453024],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001156241,"threshold_uncertainty_score":0.003867984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004017849774805509,"score_gpt":0.1925306503141927,"score_spread":0.1885128005393872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}