{"id":"W2912394746","doi":"10.1177/1203475418824079","title":"The Use of Janus Kinase Inhibitors in Alopecia Areata: A Review of the Literature","year":2019,"lang":"en","type":"review","venue":"Journal of Cutaneous Medicine and Surgery","topic":"Hair Growth and Disorders","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; Probity Medical Research; Trent University; SKiN Health","funders":"","keywords":"Janus kinase; Tofacitinib; Medicine; Alopecia areata; Ruxolitinib; STAT protein; JAK-STAT signaling pathway; Hair loss; Clinical trial; Janus kinase inhibitor; Cancer research; Immunology; Pharmacology; Signal transduction; Internal medicine; STAT3; Cytokine; Dermatology; Tyrosine kinase; Receptor; Biology; Rheumatoid arthritis; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001399486,0.0003488293,0.003931325,0.0004416954,0.00003856283,0.0000120776,0.0001934175,0.0002441479,0.00002695814],"category_scores_gemma":[0.00553217,0.0001381933,0.001014051,0.0009157311,0.0002876819,0.00007704697,0.00004916595,0.0009812418,9.570435e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004868262,"about_ca_system_score_gemma":0.001049876,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002053055,"about_ca_topic_score_gemma":0.00001142277,"domain_scores_codex":[0.9959825,0.0004030937,0.00244384,0.0001707586,0.0007489868,0.0002508061],"domain_scores_gemma":[0.9932271,0.003630357,0.002015502,0.0005089204,0.0004426222,0.0001755232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001470345,0.00008597905,0.0008121373,0.1647127,0.0002551275,0.001613767,0.0002348478,2.078541e-7,0.000001352227,0.00001029478,0.09300584,0.7391207],"study_design_scores_gemma":[0.0001848134,0.0001346072,0.00002018938,0.3879529,0.0009618164,0.006490314,0.00004881813,2.642735e-7,5.553967e-7,0.000007026955,0.6041301,0.00006863416],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004514882,0.995802,4.561046e-7,0.002023188,0.0008072384,0.0006448924,0.00001517153,0.000002098358,0.0002534118],"genre_scores_gemma":[0.0001743241,0.9978809,0.000008183129,0.001060726,0.0004426928,0.000003569644,0.0000146389,0.00002900929,0.0003860058],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7390521,"threshold_uncertainty_score":0.6622924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0772192519913791,"score_gpt":0.3199971020756233,"score_spread":0.2427778500842442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}