{"id":"W2912497666","doi":"10.1016/j.jvacx.2019.100009","title":"rVSVΔG-ZEBOV-GP (also designated V920) recombinant vesicular stomatitis virus pseudotyped with Ebola Zaire Glycoprotein: Standardized template with key considerations for a risk/benefit assessment","year":2019,"lang":"en","type":"article","venue":"Vaccine X","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Public Health Agency of Canada","keywords":"Virology; Vesicular stomatitis virus; Ebolavirus; Vector (molecular biology); Ebola virus; Ebola vaccine; Attenuated vaccine; Biology; Viral vector; Recombinant DNA; Virus; Virulence; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006269255,0.0003806366,0.0007837191,0.0003110244,0.0004997863,0.0001555794,0.00009145225,0.0001589471,0.001230549],"category_scores_gemma":[0.0001235024,0.0002545166,0.0001483136,0.0005004021,0.0000378673,0.0002491003,0.00004807539,0.0004593524,0.00009071902],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002744458,"about_ca_system_score_gemma":0.0006544177,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001282886,"about_ca_topic_score_gemma":0.001254594,"domain_scores_codex":[0.9976339,0.0001410475,0.0004912866,0.0005967919,0.0005539162,0.0005830634],"domain_scores_gemma":[0.9976934,0.0002839542,0.00024886,0.0006295541,0.0008731966,0.0002710258],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03597128,0.004701158,0.1791107,0.002663035,0.008374076,0.001857246,0.001482333,0.005194116,0.6895065,0.009493195,0.03862986,0.02301656],"study_design_scores_gemma":[0.1684299,0.06723602,0.2832296,0.00457274,0.003331826,0.004030588,0.001091399,0.04352708,0.3768482,0.005296653,0.03865347,0.003752569],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9770434,0.0001736766,0.01426756,0.00135178,0.0001488214,0.004968262,0.0001794385,0.0002408984,0.001626172],"genre_scores_gemma":[0.9795635,0.0001366048,0.01682711,0.0001836766,0.0000786759,0.0005818407,0.0001110732,0.0001022543,0.002415219],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3126583,"threshold_uncertainty_score":0.9999907,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01518067380341652,"score_gpt":0.292644408841895,"score_spread":0.2774637350384785,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}