{"id":"W2912551414","doi":"10.1172/jci.insight.124575","title":"Mycophenolate mofetil reduces STAT3 phosphorylation in systemic lupus erythematosus patients","year":2019,"lang":"en","type":"article","venue":"JCI Insight","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Allergy and Infectious Diseases; National Center for Research Resources; National Institute of General Medical Sciences; National Institutes of Health","keywords":"Mycophenolate; Mycophenolic acid; Lupus nephritis; Medicine; Immunology; Immune system; Systemic lupus erythematosus; Lupus erythematosus; Nephritis; Disease; Internal medicine; Antibody; Transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001105763,0.000186737,0.0002436365,0.0001875299,0.0001284332,0.0001384944,0.00006498186,0.0002357168,0.001283163],"category_scores_gemma":[0.0002051941,0.00006604604,0.000182119,0.0001032424,0.00006131149,0.00006682445,0.00007031318,0.0002643848,0.0001890387],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001016458,"about_ca_system_score_gemma":0.000108066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004365206,"about_ca_topic_score_gemma":0.000977893,"domain_scores_codex":[0.9999259,0.00002238412,0.000008331152,0.000008348188,0.00001511019,0.00001998707],"domain_scores_gemma":[0.999904,0.00001984317,0.00002755979,0.000004678923,0.000009756736,0.00003415072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02350319,0.001375986,0.1210327,0.0004165475,0.0002290602,0.001695068,0.0002068374,0.0003008755,0.7060212,0.0001071374,0.002071605,0.1430397],"study_design_scores_gemma":[0.001591403,0.01756136,0.8088237,0.0001097268,0.0003849799,0.006597058,0.0002057849,0.001764618,0.1533983,0.0001899741,0.009351181,0.00002188447],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968351,0.002104461,0.0001281065,0.00009983181,0.00002113686,0.00001083787,0.000117641,0.00002546115,0.0006574516],"genre_scores_gemma":[0.99889,0.0003640082,0.0001809648,0.00009365757,0.00001191971,0.000008728227,0.0001135449,0.000002238723,0.000334949],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001283163,"threshold_uncertainty_score":0.004292607,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0139600774806376,"score_gpt":0.2623282671648597,"score_spread":0.2483681896842221,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}