{"id":"W2912684103","doi":"10.1038/s41586-018-0849-9","title":"Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease","year":2019,"lang":"en","type":"article","venue":"Nature","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":171,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; Banting and Best Diabetes Centre, University of Toronto; Canadian Institutes of Health Research; National Institutes of Health; Vetenskapsrådet; American Heart Association; Novo Nordisk; Austrian Science Fund; Canada Research Chairs; Deutsche Forschungsgemeinschaft","keywords":"Intraepithelial lymphocyte; Immune system; Small intestine; Biology; Anabolism; Endocrinology; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002358737,0.0005166371,0.0002757215,0.0003217054,0.0001719151,0.0006923335,0.0001538032,0.0006416857,0.002613482],"category_scores_gemma":[0.0004387542,0.0002353278,0.0002859211,0.0001513,0.0002989552,0.0003153284,0.0004028672,0.001176059,0.0004949843],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002616065,"about_ca_system_score_gemma":0.0001455501,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002524482,"about_ca_topic_score_gemma":0.0003781453,"domain_scores_codex":[0.9998474,0.00004830949,0.000007546016,0.00003462808,0.00002604189,0.00003611109],"domain_scores_gemma":[0.9997659,0.0000352446,0.00006225799,0.0000303469,0.0000322514,0.00007394335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003823987,0.0001761818,0.01826198,0.0002146694,0.00009358326,0.001057924,0.0001021889,0.0003953209,0.9324448,0.002107847,0.001475286,0.03984628],"study_design_scores_gemma":[0.001121627,0.004388448,0.4655872,0.0002164096,0.0007206628,0.005097009,0.0009032243,0.006368885,0.4562094,0.01036399,0.04893155,0.00009162645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9772993,0.008781746,0.004807672,0.001271681,0.000703163,0.00003455875,0.0003358061,0.000295116,0.006470781],"genre_scores_gemma":[0.9888434,0.002734543,0.002906504,0.0004064993,0.0002925287,0.00002704879,0.0001305084,0.00005766056,0.004601134],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002613482,"threshold_uncertainty_score":0.008742988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002558292264346096,"score_gpt":0.1921431682905408,"score_spread":0.1895848760261948,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}