{"id":"W2912739876","doi":"10.1007/s40265-018-1024-1","title":"l-Ornithine l-Aspartate (LOLA) for Hepatic Encephalopathy in Cirrhosis: Results of Randomized Controlled Trials and Meta-Analyses","year":2019,"lang":"en","type":"review","venue":"Drugs","topic":"Liver Disease and Transplantation","field":"Medicine","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Merz Pharmaceuticals; King's College London; National Institute for Health and Care Research; NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research","keywords":"Medicine; Hepatic encephalopathy; Randomized controlled trial; Cirrhosis; Internal medicine; Portosystemic shunt; Portal hypertension; Meta-analysis; Transjugular intrahepatic portosystemic shunt; Concomitant; Lactulose; Gastroenterology; Intensive care medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_broad"],"consensus_categories":[],"category_scores_codex":[0.009134606,0.0004597655,0.02770001,0.0005454724,0.00002119257,0.0000212915,0.0000943131,0.0001960543,0.00003975008],"category_scores_gemma":[0.002217481,0.0002341005,0.00526418,0.0002223551,0.00006955882,0.00007137215,0.00001097398,0.0001640779,0.00001020271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002560179,"about_ca_system_score_gemma":0.0003264581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001138152,"about_ca_topic_score_gemma":0.00000730266,"domain_scores_codex":[0.9930226,0.002277545,0.003690274,0.0004425363,0.0003663732,0.0002006887],"domain_scores_gemma":[0.9842486,0.01292171,0.002208637,0.0003367468,0.0001829352,0.0001013197],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.5246653,0.0003583233,0.000007141474,0.1445888,0.257925,0.00003898736,0.003053741,0.000007957752,0.00001365362,0.0001712558,0.0001511888,0.0690187],"study_design_scores_gemma":[0.3655624,0.0000847736,0.000001864619,0.004541676,0.6241847,0.000003010686,0.00003801223,0.00006399698,0.0000183736,0.0001000617,0.005232493,0.0001685873],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000128207,0.9857993,0.00007563253,0.00007020634,0.000104912,0.01241413,0.001010585,0.0000165369,0.0003804508],"genre_scores_gemma":[0.003619675,0.9916637,0.0001779643,0.00005689098,0.0000769196,0.002529416,0.001173428,0.00003460684,0.0006674326],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.3662598,"threshold_uncertainty_score":0.9867348,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2483490198769808,"score_gpt":0.4534745076328866,"score_spread":0.2051254877559058,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}