{"id":"W2912754100","doi":"10.1093/infdis/jiy537","title":"Protective Efficacy and Long-Term Immunogenicity in Cynomolgus Macaques by Ebola Virus Glycoprotein Synthetic DNA Vaccines","year":2018,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; University of Manitoba; Public Health Agency of Canada","funders":"Defense Advanced Research Projects Agency; INOVIO Pharmaceuticals","keywords":"Immunogenicity; Ebola virus; DNA vaccination; Virology; Vaccination; Ebola vaccine; Medicine; Immune system; Immunology; Adjuvant; Virus; Immunity; Immunization; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003524437,0.0002955345,0.0001796581,0.0002700398,0.0001298805,0.0002263968,0.0001547747,0.0003514257,0.0006126842],"category_scores_gemma":[0.0003599824,0.00008271584,0.0001583625,0.00007677571,0.0002913395,0.0002175357,0.0001510487,0.0003856077,0.0001548443],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003197851,"about_ca_system_score_gemma":0.0001986905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006049396,"about_ca_topic_score_gemma":0.0007328252,"domain_scores_codex":[0.9998727,0.00002904236,0.00001013111,0.00002533849,0.0000264382,0.00003629527],"domain_scores_gemma":[0.999844,0.00002892442,0.00004588239,0.00001931911,0.00003170624,0.00003021832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004416843,0.0001565077,0.00130421,0.00007031875,0.00001400804,0.00003484555,0.00005646279,0.0001284562,0.9933848,0.00006208703,0.00005205918,0.004294608],"study_design_scores_gemma":[0.0003947696,0.03428329,0.07065611,0.000125859,0.0002039928,0.001356339,0.0002412053,0.004102991,0.8799576,0.0004685419,0.008183655,0.00002565586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978294,0.0008742764,0.0007815852,0.00007026472,0.000009899238,0.00003440646,0.00008162177,0.00002483203,0.0002937256],"genre_scores_gemma":[0.9972969,0.0004606403,0.001097263,0.00007414015,0.00001267096,0.00008965699,0.0002853666,0.000008396554,0.0006749398],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006126842,"threshold_uncertainty_score":0.00232017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01051999796017803,"score_gpt":0.3000808468693541,"score_spread":0.289560848909176,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}