{"id":"W2912801489","doi":"10.1002/cpnc.75","title":"6‐Phenylpyrrolocytidine: An Intrinsically Fluorescent, Environmentally Responsive Nucleoside Analogue","year":2019,"lang":"en","type":"article","venue":"Current Protocols in Nucleic Acid Chemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Phosphoramidite; Sonogashira coupling; Nucleoside; Chemistry; Combinatorial chemistry; Reagent; Oligonucleotide; Nucleobase; Nucleotide; Stereochemistry; Catalysis; Organic chemistry; Biochemistry; DNA; Palladium","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001609463,0.0003005424,0.0002106795,0.0001007101,0.0001248694,0.0002307308,0.0003578924,0.0003484416,0.001195412],"category_scores_gemma":[0.000156579,0.0001408248,0.00008875922,0.0001287726,0.0001970405,0.0001564662,0.0002213972,0.0005120592,0.0007935926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000198653,"about_ca_system_score_gemma":0.0001662546,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003768433,"about_ca_topic_score_gemma":0.0006995288,"domain_scores_codex":[0.999827,0.00004023878,0.000009592229,0.00005953057,0.00003139725,0.00003243623],"domain_scores_gemma":[0.999885,0.00002531284,0.00002631542,0.0000164543,0.00001764871,0.00002927204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003636662,0.000005378793,0.00001464248,0.00003330502,8.981299e-7,0.00005281969,0.000009247139,0.00006542053,0.9987084,0.0001263077,0.00003416823,0.0009130947],"study_design_scores_gemma":[0.000007604844,0.0001311072,0.0002204609,0.000002722956,0.00000429391,0.0001328179,0.000003867976,0.0002743766,0.9955192,0.00001618653,0.003683812,0.000003703365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.9345937,0.00485127,0.04672304,0.0002036219,0.0001514286,0.0001249114,0.0008440616,0.0007603966,0.01174757],"genre_scores_gemma":[0.9682408,0.00125397,0.0256855,0.00006953912,0.00002692607,0.00005631229,0.0003783951,0.00008315769,0.004205484],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001195412,"threshold_uncertainty_score":0.003998995,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01124961423945187,"score_gpt":0.3007683393469373,"score_spread":0.2895187251074854,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}