{"id":"W2912801489","doi":"10.1002/cpnc.75","title":"6‐Phenylpyrrolocytidine: An Intrinsically Fluorescent, Environmentally Responsive Nucleoside Analogue","year":2019,"lang":"en","type":"article","venue":"Current Protocols in Nucleic Acid Chemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Phosphoramidite; Sonogashira coupling; Nucleoside; Chemistry; Combinatorial chemistry; Reagent; Oligonucleotide; Nucleobase; Nucleotide; Stereochemistry; Catalysis; Organic chemistry; Biochemistry; DNA; Palladium","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002875714,0.0003997911,0.0003708944,0.0000618316,0.00007044838,0.00005244572,0.0005811916,0.0003276899,0.00005939359],"category_scores_gemma":[0.0001114482,0.0003867794,0.0001743316,0.0002022371,0.0002112121,0.00002188155,0.0003528622,0.0004233329,0.00003302628],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001243262,"about_ca_system_score_gemma":0.0001004728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002633447,"about_ca_topic_score_gemma":0.000005471475,"domain_scores_codex":[0.9976067,0.00009736451,0.0005212962,0.0009725344,0.0003027042,0.0004994282],"domain_scores_gemma":[0.9984128,0.00001167435,0.0002357183,0.001075562,0.0000729841,0.0001912194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004690989,0.0004130006,0.008144697,0.0001089472,0.00002580483,0.000009482101,0.0000189697,0.00001114633,0.9804766,0.00001309693,0.0003722796,0.009936944],"study_design_scores_gemma":[0.001090277,0.0002962607,0.00200712,0.0001774885,0.00001486254,0.00002120688,0.00006275103,0.0001380379,0.9595009,0.00009444213,0.03609749,0.0004991673],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902149,0.0001150106,0.0001757792,0.00006790211,0.00005214883,0.008616709,0.00004583089,0.00008523732,0.0006264617],"genre_scores_gemma":[0.9936332,0.00009118646,0.002241805,0.0001397565,0.000254072,0.003040606,0.0003795953,0.00005793771,0.0001618515],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03572521,"threshold_uncertainty_score":0.9998584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01124961423945187,"score_gpt":0.3007683393469373,"score_spread":0.2895187251074854,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}