{"id":"W2912809798","doi":"10.1093/ecco-jcc/jjy222.420","title":"P296 Effect of upadacitinib on patient-reported symptoms by the new Ulcerative Colitis Symptoms Questionnaire (UC-SQ) in patients with moderate to severe ulcerative colitis: data from the Phase 2b study U-ACHIEVE","year":2019,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Ulcerative colitis; Medicine; Internal medicine; Gastroenterology; Placebo; Defecation; Inflammatory bowel disease; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00120272,0.0004112696,0.001818163,0.0001954944,0.0002431869,0.0005758209,0.0003502327,0.0006570153,0.004601772],"category_scores_gemma":[0.001434554,0.0002100603,0.00136121,0.0003335417,0.0002690124,0.0005729205,0.000339715,0.001510526,0.0007493636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002539992,"about_ca_system_score_gemma":0.0004780049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006897729,"about_ca_topic_score_gemma":0.002528729,"domain_scores_codex":[0.9994838,0.0002504218,0.00004986747,0.00006841427,0.00008958911,0.00005775032],"domain_scores_gemma":[0.9993373,0.0002164115,0.0001636731,0.00004270548,0.00006490982,0.0001749688],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7379159,0.01033415,0.01294265,0.003540868,0.003842777,0.0002926272,0.0001622926,0.00312147,0.0365396,0.0002928341,0.01700487,0.1740099],"study_design_scores_gemma":[0.4917976,0.3047952,0.1648727,0.0003509953,0.003490574,0.001138722,0.0001665803,0.006326747,0.007541557,0.0008084758,0.01855486,0.0001558356],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9724974,0.01277012,0.0004986121,0.0007588807,0.0001999761,0.0008825624,0.006909207,0.00014007,0.005343165],"genre_scores_gemma":[0.9885625,0.002887052,0.0005495584,0.000574352,0.00007361091,0.0005322853,0.005130791,0.00001818105,0.001671695],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004601772,"threshold_uncertainty_score":0.01539445,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006072589167392768,"score_gpt":0.2530318838311084,"score_spread":0.2469592946637156,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}