{"id":"W2912834264","doi":"","title":"Natural Killer Cell as Effectors in Chimeric Antigen Receptor Based Immunotherapies for Cancer","year":2019,"lang":"en","type":"dissertation","venue":"MacSphere (McMaster University)","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; McMaster University","keywords":"Chimeric antigen receptor; Effector; Receptor; Cancer; Immunotherapy; Antigen; Immunology; Cancer research; Biology; Immune system; Biochemistry; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003413284,0.0002729792,0.0003226108,0.0002463629,0.000093724,0.0004457235,0.0003195547,0.0005820562,0.0011344],"category_scores_gemma":[0.0001248419,0.0001347027,0.0002450805,0.000134327,0.0002866813,0.0003812901,0.0003666179,0.0007011263,0.000810638],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002784753,"about_ca_system_score_gemma":0.0002305621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001858471,"about_ca_topic_score_gemma":0.0002440885,"domain_scores_codex":[0.9998146,0.00005196039,0.00001067959,0.00002958807,0.00005903767,0.0000341351],"domain_scores_gemma":[0.9999644,0.000009466265,0.000005849916,0.000006155195,0.000007753073,0.000006420527],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002531847,0.0001350823,0.000143476,0.0004216851,0.00001340475,0.0002783348,0.00008052668,0.001263961,0.9518163,0.003943109,0.0004862518,0.04116469],"study_design_scores_gemma":[0.0001197775,0.001925098,0.0007431921,0.0000664234,0.00006116737,0.002322533,0.00003723259,0.003786051,0.8673249,0.001723299,0.1218697,0.00002053427],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.661079,0.1446636,0.1660953,0.001378578,0.0009974919,0.001012993,0.0004954868,0.00130952,0.02296809],"genre_scores_gemma":[0.9035873,0.03645291,0.0398013,0.0004212922,0.0001030644,0.000422459,0.0004993452,0.0001006513,0.0186117],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0011344,"threshold_uncertainty_score":0.003794909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005748743103833342,"score_gpt":0.2100276132790912,"score_spread":0.2042788701752578,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}