{"id":"W2912906332","doi":"10.1007/s40265-019-1055-2","title":"Cefiderocol: A Siderophore Cephalosporin with Activity Against Carbapenem-Resistant and Multidrug-Resistant Gram-Negative Bacilli","year":2019,"lang":"en","type":"review","venue":"Drugs","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":429,"is_retracted":false,"has_abstract":false,"ca_institutions":"Manitoba Health; University of Manitoba","funders":"","keywords":"Cephalosporin; Siderophore; Microbiology; Bacilli; Carbapenem; Multiple drug resistance; Medicine; Gram; Drug resistance; Pharmacotherapy; Antibiotics; Biology; Bacteria; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002805836,0.001164815,0.002125186,0.000136401,0.0001918487,0.0001555183,0.0005490598,0.0007770121,0.00001969099],"category_scores_gemma":[0.0001109171,0.0008964518,0.0004703433,0.0002832137,0.000451851,0.0000163986,0.0003798562,0.0005267893,0.00004590266],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001657879,"about_ca_system_score_gemma":0.0006872748,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001478316,"about_ca_topic_score_gemma":0.0002826752,"domain_scores_codex":[0.9960575,0.0003363609,0.0007005834,0.001674281,0.0004573589,0.0007739482],"domain_scores_gemma":[0.9971849,0.0001518482,0.0008283073,0.001380142,0.0001787625,0.0002760372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002462362,0.000614153,0.0003030338,0.03868068,0.003375703,0.0003771578,0.0005815347,0.000008464054,0.03439127,0.0002001468,0.001730338,0.9172751],"study_design_scores_gemma":[0.001196016,0.0005822992,0.0004218455,0.006429608,0.0008439074,0.00003187318,0.000301497,0.000005207633,0.002176713,0.00001276035,0.9863127,0.001685561],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.08321029,0.9108536,0.00003722874,0.00002581392,0.000274582,0.002778029,0.0005706947,0.00005255037,0.002197177],"genre_scores_gemma":[0.03555406,0.9601442,0.0009135241,0.0000661218,0.000268301,0.0001407059,0.0005426012,0.0002442794,0.002126219],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9845824,"threshold_uncertainty_score":0.9993486,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02029146034473697,"score_gpt":0.281665191329291,"score_spread":0.2613737309845541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}