{"id":"W2912951041","doi":"10.1182/blood-2018-99-110258","title":"Donor T Cells Require Notch Signals but Not Alloantigen Presentation from Specialized Secondary Lymphoid Organ Fibroblasts to Drive Graft-Versus-Host Disease","year":2018,"lang":"en","type":"article","venue":"Blood","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Reticular cell; Stromal cell; Bone marrow; Biology; Haematopoiesis; Immunology; High endothelial venules; T cell; Myeloid; Lymphatic system; Stem cell; Pathology; Cancer research; Cell biology; Immune system; Spleen; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001005603,0.0002324012,0.0001580358,0.0001619919,0.0001217957,0.0003384662,0.0001271546,0.0003044667,0.001993722],"category_scores_gemma":[0.00006265258,0.0001192908,0.0002347188,0.00008750834,0.0001467701,0.0001791518,0.0002238326,0.0008354874,0.0005713555],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001762115,"about_ca_system_score_gemma":0.0001305511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002665099,"about_ca_topic_score_gemma":0.0005553518,"domain_scores_codex":[0.9998351,0.00001803742,0.00001967442,0.0000380531,0.00004862709,0.00004042007],"domain_scores_gemma":[0.9998838,0.00001086023,0.00003793965,0.00001321453,0.00001250432,0.0000417579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002636941,0.00001173659,0.0001539178,0.00001006854,0.000001124948,0.00002690784,0.000005724356,0.0000108828,0.9994484,0.00004504535,0.00001225014,0.0002476413],"study_design_scores_gemma":[0.00001387871,0.0001736182,0.004436984,0.000006734143,0.00001185665,0.0003953649,0.00004115685,0.0003740866,0.9929294,0.00003550826,0.001579166,0.000002394051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946039,0.0005123408,0.002550097,0.00006199486,0.0000239482,0.00002651253,0.0004657279,0.000056629,0.001698823],"genre_scores_gemma":[0.9946713,0.0002708651,0.001360267,0.00006683556,0.00000721231,0.00003372721,0.0005105449,0.00002081213,0.003058385],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001993722,"threshold_uncertainty_score":0.006669641,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01288481080456245,"score_gpt":0.2350656122735866,"score_spread":0.2221808014690242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}