{"id":"W2913005264","doi":"10.1371/journal.pone.0210646","title":"A comparison of the Muenster, SIOP Boston, Brock, Chang and CTCAEv4.03 ototoxicity grading scales applied to 3,799 audiograms of childhood cancer patients treated with platinum-based chemotherapy","year":2019,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Ear and Head Tumors","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Children's Hospital","funders":"Seventh Framework Programme; Stichting Kinder Oncologisch Centrum Rotterdam; European Commission","keywords":"Audiogram; Ototoxicity; Concordance; Medicine; Hearing loss; Audiology; Common Terminology Criteria for Adverse Events; Adverse effect; Oncology; Internal medicine; Chemotherapy; Cisplatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003773879,0.0002722185,0.0003794038,0.002062115,0.0002340262,0.0005178556,0.0003990913,0.0003564386,0.0006238921],"category_scores_gemma":[0.01075857,0.0001413732,0.0007413349,0.00104715,0.0002688889,0.0004749136,0.0008928564,0.0002907036,0.0001507378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000522287,"about_ca_system_score_gemma":0.0004025344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003054565,"about_ca_topic_score_gemma":0.007161457,"domain_scores_codex":[0.9969442,0.0008378151,0.0006625776,0.0003463966,0.001061389,0.0001476026],"domain_scores_gemma":[0.9902226,0.0031559,0.003461171,0.0005298581,0.00211691,0.0005136456],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005352396,0.0000362969,0.9825272,0.00006067814,0.0002336079,0.00005335741,0.0002633771,0.0002683403,0.0006844321,0.00003452502,0.0003426742,0.0149602],"study_design_scores_gemma":[0.00002292657,0.0002695565,0.9983537,0.00001301468,0.00005236696,0.0001602027,0.0001151527,0.0004370548,0.0002460834,0.00002054772,0.0003032307,0.000006107712],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967528,0.0005607007,0.0004880992,0.00003293914,0.00002299728,0.0000660658,0.0005543823,0.00001406053,0.001508015],"genre_scores_gemma":[0.9976873,0.0001897353,0.0007056054,0.00001645375,0.00001185727,0.00005620088,0.001061727,0.00000566992,0.0002653606],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003773879,"threshold_uncertainty_score":0.01995844,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02458855604499519,"score_gpt":0.2580951066333485,"score_spread":0.2335065505883533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}