{"id":"W2913024223","doi":"10.1002/cphg.50","title":"Matchmaker Exchange","year":2017,"lang":"en","type":"article","venue":"Current Protocols in Human Genetics","topic":"Genomics and Rare Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Eastern Ontario; University of Ottawa; Hospital for Sick Children","funders":"National Human Genome Research Institute; National Institutes of Health","keywords":"DECIPHER; Computational biology; Biology; Genomics; Genetics; Gene; Genome; Phenotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001243091,0.0001661656,0.0001317308,0.00003811615,0.0002667616,0.00014387,0.0005945864,0.00009377715,0.00005367552],"category_scores_gemma":[0.00003250313,0.0001658078,0.00007973101,0.00001724296,0.0001222989,0.000003296817,0.0003972479,0.00009431545,0.00001654614],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001374537,"about_ca_system_score_gemma":0.00005203248,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004089931,"about_ca_topic_score_gemma":0.00004237254,"domain_scores_codex":[0.9990052,0.00002967821,0.0002214641,0.000355266,0.0001119461,0.0002764383],"domain_scores_gemma":[0.9987129,0.000001859004,0.0001455292,0.0009907879,0.00005584784,0.00009309452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003124932,0.00237464,0.4973237,0.001589299,0.0001125624,0.00009481428,0.0004959875,0.0003405661,0.3153082,0.001716981,0.03186679,0.1484639],"study_design_scores_gemma":[0.002137447,0.0003603108,0.1784225,0.0001915818,0.00001455973,0.00000816569,0.0000215799,0.00005739931,0.04588991,0.001673643,0.7706006,0.0006222529],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9724385,0.001645907,0.0001754024,0.00004561304,0.000334033,0.02273402,0.0000479222,0.00001337418,0.002565255],"genre_scores_gemma":[0.9742193,0.0001741004,0.00018377,0.00004558153,0.0006134783,0.02415398,0.00008616309,0.00003715587,0.0004865118],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7387338,"threshold_uncertainty_score":0.6761447,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06276739396268333,"score_gpt":0.3937303247269309,"score_spread":0.3309629307642476,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}