{"id":"W2913070802","doi":"10.1002/chin.200035127","title":"ChemInform Abstract: Pyrrolo[3,2,1‐ij]quinoline Derivatives, a 5‐HT<sub>2c</sub> Receptor Agonist with Selectivity over the 5‐HT<sub>2a</sub> Receptor: Potential Therapeutic Applications for Epilepsy and Obesity.","year":2000,"lang":"en","type":"article","venue":"ChemInform","topic":"Cyclopropane Reaction Mechanisms","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"IDELIX Software (Canada)","funders":"","keywords":"Chemistry; Quinoline; Agonist; 5-HT receptor; Selectivity; Receptor; Combinatorial chemistry; Stereochemistry; Organic chemistry; Serotonin; Biochemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000338072,0.0008730299,0.0006905283,0.0001074182,0.0009051666,0.0002940462,0.0006538756,0.000626428,0.002493264],"category_scores_gemma":[0.0000574796,0.000718123,0.000311272,0.0005143524,0.0004975727,0.0006939055,0.0001347409,0.0009591407,0.0002430354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005029404,"about_ca_system_score_gemma":0.0003560159,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002184632,"about_ca_topic_score_gemma":0.00007841919,"domain_scores_codex":[0.996418,0.00000133959,0.0008574685,0.0009426209,0.0006978434,0.001082735],"domain_scores_gemma":[0.9972462,0.0002615121,0.0006320025,0.001107924,0.0003713159,0.0003810585],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004598615,0.0002078302,0.00004303631,0.0003658461,0.0001765085,0.000001297011,0.0006616029,0.00000256529,0.5470457,0.00007282635,0.002618398,0.4483445],"study_design_scores_gemma":[0.001760881,0.0001050256,0.0007203321,0.00008218437,0.0001695515,0.00009959792,0.0005777868,0.00004852526,0.8214798,0.0001577558,0.1740168,0.0007817429],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.878451,0.0007488675,0.0001232533,0.0004957025,0.0001304791,0.002530009,0.0006024443,0.0007183541,0.1161999],"genre_scores_gemma":[0.9881494,0.001281801,0.0002564442,0.000393684,0.0009735968,0.001983719,0.001459508,0.0002072945,0.005294563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4475628,"threshold_uncertainty_score":0.999527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00794677309243055,"score_gpt":0.2181774584199218,"score_spread":0.2102306853274912,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}