{"id":"W2913070802","doi":"10.1002/chin.200035127","title":"ChemInform Abstract: Pyrrolo[3,2,1‐ij]quinoline Derivatives, a 5‐HT<sub>2c</sub> Receptor Agonist with Selectivity over the 5‐HT<sub>2a</sub> Receptor: Potential Therapeutic Applications for Epilepsy and Obesity.","year":2000,"lang":"en","type":"article","venue":"ChemInform","topic":"Cyclopropane Reaction Mechanisms","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"IDELIX Software (Canada)","funders":"","keywords":"Chemistry; Quinoline; Agonist; 5-HT receptor; Selectivity; Receptor; Combinatorial chemistry; Stereochemistry; Organic chemistry; Serotonin; Biochemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001111365,0.0007727867,0.0002480077,0.0005211478,0.0003252699,0.0004916888,0.0004571422,0.0004489914,0.10673],"category_scores_gemma":[0.0001443687,0.0001903019,0.0002050571,0.0005163786,0.0001461272,0.0005583802,0.0002488714,0.0006498363,0.02393144],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005210558,"about_ca_system_score_gemma":0.0004454887,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007949562,"about_ca_topic_score_gemma":0.001089624,"domain_scores_codex":[0.9999491,0.000003967995,0.000001880346,0.00001010892,0.00002615026,0.000008781011],"domain_scores_gemma":[0.9999607,0.00000551493,0.000009852271,0.000002964749,0.000008839541,0.00001220104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001409652,0.0003361713,0.0004526176,0.003500434,0.00008510692,0.0009014726,0.00007741377,0.001362634,0.449731,0.01672202,0.2498347,0.2755869],"study_design_scores_gemma":[0.0003732392,0.0008280286,0.002994895,0.0001557016,0.00009472155,0.001037524,0.00003179508,0.001492916,0.3661178,0.002448647,0.6243834,0.00004129185],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.1204392,0.1013165,0.02618642,0.007790516,0.006185024,0.0006487928,0.01842913,0.004111871,0.7148926],"genre_scores_gemma":[0.3614357,0.06520227,0.009566202,0.001771683,0.00185062,0.0001805504,0.01260758,0.0003715279,0.5470139],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.10673,"threshold_uncertainty_score":0.3570473,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00794677309243055,"score_gpt":0.2181774584199218,"score_spread":0.2102306853274912,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}