{"id":"W2913130398","doi":"10.1113/jp276807","title":"Physiological roles and molecular mechanisms of K<sup>+</sup>‐Cl<sup>−</sup> cotransport in the mammalian kidney and cardiovascular system: where are we?","year":2019,"lang":"en","type":"review","venue":"The Journal of Physiology","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Cotransporter; Gene isoform; Distal convoluted tubule; Kidney; Symporter; Chemistry; Cell biology; Transporter; Proximal tubule; Endocrinology; Internal medicine; Biology; Biochemistry; Medicine; Gene; Reabsorption; Sodium","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000401709,0.0004332652,0.001115708,0.000609185,0.0002741009,0.001533158,0.0005811171,0.0009561933,0.001274778],"category_scores_gemma":[0.0002520036,0.0001801535,0.0003380738,0.000687999,0.0006098446,0.001854031,0.0005205634,0.001047121,0.000974632],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004430267,"about_ca_system_score_gemma":0.0008506788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006206929,"about_ca_topic_score_gemma":0.0005025865,"domain_scores_codex":[0.9998512,0.00002650807,0.0000266698,0.00003403418,0.000033557,0.00002791506],"domain_scores_gemma":[0.9998343,0.0000350954,0.00004308278,0.000006432918,0.0000594051,0.00002179042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001018546,0.0001325817,0.001373178,0.03348846,0.000231126,0.001692833,0.0005595788,0.001606167,0.1173368,0.02099184,0.02539579,0.796173],"study_design_scores_gemma":[0.00005245064,0.0005533141,0.008276982,0.003264222,0.0004466211,0.003722306,0.0009535675,0.001367181,0.02310898,0.01724073,0.9408624,0.000151173],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00196772,0.9953101,0.0008408206,0.0008233535,0.0002547986,0.000004269789,0.00003797601,0.00002013051,0.0007408209],"genre_scores_gemma":[0.01096724,0.9867256,0.0004261379,0.0004307789,0.0004193321,0.00001181588,0.00005474248,0.0000056695,0.0009588085],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001533158,"threshold_uncertainty_score":0.004264534,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01983650823295638,"score_gpt":0.2457963826402768,"score_spread":0.2259598744073204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}