{"id":"W2913130398","doi":"10.1113/jp276807","title":"Physiological roles and molecular mechanisms of K<sup>+</sup>‐Cl<sup>−</sup> cotransport in the mammalian kidney and cardiovascular system: where are we?","year":2019,"lang":"en","type":"review","venue":"The Journal of Physiology","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Cotransporter; Gene isoform; Distal convoluted tubule; Kidney; Symporter; Chemistry; Cell biology; Transporter; Proximal tubule; Endocrinology; Internal medicine; Biology; Biochemistry; Medicine; Gene; Reabsorption; Sodium","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001043489,0.0004798759,0.001901409,0.0001120533,0.00007684503,0.00001146784,0.0006083956,0.0006361398,0.0000117544],"category_scores_gemma":[0.00001902914,0.0002587341,0.0008703095,0.0001492451,0.0002620494,0.00001046118,0.0000741338,0.0005123956,0.000001846314],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001860625,"about_ca_system_score_gemma":0.00014859,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000157766,"about_ca_topic_score_gemma":0.000003300259,"domain_scores_codex":[0.9970902,0.0009812108,0.0008939086,0.0003899748,0.0003163473,0.0003283366],"domain_scores_gemma":[0.9983708,0.00005219601,0.00071485,0.0006135518,0.0001462502,0.0001023313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.004147157,0.002056229,0.0003102289,0.2527632,0.02739795,0.0009793337,0.007030929,0.0912172,0.4918956,0.00828625,0.007889649,0.1060262],"study_design_scores_gemma":[0.007790411,0.006251763,0.001705598,0.03448928,0.02039,0.005574482,0.01424871,0.001314657,0.01143891,0.00390446,0.8893786,0.003513142],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.07271565,0.9258094,0.0004926283,0.0001428929,0.000090464,0.0006276912,0.00008985362,0.000004674806,0.00002669421],"genre_scores_gemma":[0.3611222,0.6384076,0.00002938965,0.00006712014,0.0002174053,0.00001197705,0.00009956571,0.00003194506,0.00001284767],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8814889,"threshold_uncertainty_score":0.9999865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01983650823295638,"score_gpt":0.2457963826402768,"score_spread":0.2259598744073204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}