{"id":"W2913155528","doi":"10.1016/j.neuron.2019.01.015","title":"Transcriptional Feedback Links Lipid Synthesis to Synaptic Vesicle Pools in Drosophila Photoreceptors","year":2019,"lang":"en","type":"article","venue":"Neuron","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; Dalhousie University","funders":"National Institute of General Medical Sciences; National Eye Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Synaptic vesicle; Biology; Cell biology; Vesicle; Axon; Synaptic vesicle recycling; Axon terminal; Neuroscience; Synapse; Sterol regulatory element-binding protein; Biochemistry; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002199557,0.0003014642,0.0003202506,0.0002379073,0.0003343755,0.001012096,0.0003538312,0.0003680072,0.001777121],"category_scores_gemma":[0.0004344329,0.000270481,0.0003452238,0.0001410864,0.0004086963,0.0007045745,0.0007603517,0.0007073295,0.0006597156],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001091829,"about_ca_system_score_gemma":0.0003287666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001475419,"about_ca_topic_score_gemma":0.003338415,"domain_scores_codex":[0.9997846,0.00002224528,0.00001532788,0.00008104443,0.00004925983,0.00004749684],"domain_scores_gemma":[0.9997072,0.000062517,0.0000567637,0.00003027926,0.00006914604,0.00007415289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001432047,0.0000120036,0.0007486259,0.00001781579,0.000003510215,0.00003341492,0.00002530864,0.000110546,0.9969132,0.0005381724,0.00007167592,0.001382563],"study_design_scores_gemma":[0.00003875459,0.0001199544,0.03595813,0.00001793305,0.00002320963,0.00007430262,0.000172487,0.006350375,0.9545534,0.001014967,0.001659967,0.00001641232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990398,0.001102468,0.004754336,0.0004527354,0.00008032366,0.00001171842,0.0004875762,0.0001204162,0.002592354],"genre_scores_gemma":[0.994796,0.0003051094,0.001091731,0.000159934,0.00001886472,0.00001212017,0.0005015114,0.00006634793,0.003048504],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001777121,"threshold_uncertainty_score":0.007921755,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02651648691057178,"score_gpt":0.2684551289844989,"score_spread":0.2419386420739271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}