{"id":"W2913202798","doi":"10.1007/s40744-019-0140-z","title":"Safety and Efficacy of Repeat Administration of Triamcinolone Acetonide Extended-release in Osteoarthritis of the Knee: A Phase 3b, Open-label Study","year":2019,"lang":"en","type":"article","venue":"Rheumatology and Therapy","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Sanofi; Musculoskeletal Transplant Foundation","keywords":"Medicine; Osteoarthritis; WOMAC; Triamcinolone acetonide; Adverse effect; Dosing; Clinical trial; Quality of life (healthcare); Surgery; Anesthesia; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00285396,0.001186934,0.002319296,0.0004199318,0.0003757444,0.0008229237,0.0008957697,0.001381646,0.003526281],"category_scores_gemma":[0.001487683,0.0005076966,0.001524825,0.0003920573,0.0006770442,0.0007956044,0.0002719531,0.002037962,0.0009487735],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004170652,"about_ca_system_score_gemma":0.0009042076,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002884887,"about_ca_topic_score_gemma":0.0007521534,"domain_scores_codex":[0.999204,0.0003594951,0.00007113168,0.0001370844,0.000128769,0.00009964612],"domain_scores_gemma":[0.998209,0.0003872196,0.0007303247,0.0002013171,0.0001501023,0.0003220872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7613273,0.08671715,0.006506263,0.001669972,0.00182723,0.0002332629,0.000258653,0.0009819189,0.04529918,0.00007947853,0.001152888,0.09394675],"study_design_scores_gemma":[0.3038635,0.6780844,0.01247631,0.0000651321,0.0004409304,0.0002675479,0.00004037797,0.0005731327,0.002964298,0.00006075439,0.001129574,0.00003399239],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934446,0.003151078,0.0006449121,0.0001288103,0.00006415113,0.001508618,0.0005041524,0.00006800958,0.0004856758],"genre_scores_gemma":[0.9914652,0.001956593,0.00156348,0.0004997402,0.0002182712,0.002271083,0.0008085698,0.00002412377,0.001193074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003526281,"threshold_uncertainty_score":0.01509339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0210760317936827,"score_gpt":0.3156357795365636,"score_spread":0.2945597477428809,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}